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Toxic Metal: The Health Dangers of Lead

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Lead is a naturally occurring metal but its natural status doesn’t mean it’s healthy. In fact, lead is extremely toxic to humans and affects the liver, kidneys, reproductive system, and nervous system. [1] Lead exposure can happen quietly and causes permanent problems, especially to the brain.Children are the most at-risk for lead exposure and the worst effects impact motor skills and cognitive impairment. Toxic metal and lead poisoning is a problem in many countries in the world including the United States, Iran, India, and China. Sources of lead exposure really vary which is due in part to the inclusion of lead in many chemicals and products. Occupational exposure is a public health issue everywhere and mine workers, paint factory employees, drivers, and tile makers are just a few occupations that have been identified as higher risk for lead toxicity. [2]

Health Dangers of Lead Exposure

Lead is harmful to nearly all systems of the body. Lead is one of many toxic metals that cause damage by inducing oxidative stress. Because lead accumulates in the body, it can simply sit there and be a constant source of harmful free radicals. What may be most scary is that the harmful effects of lead exposure are often irreversible. Lead exposure is perhaps best associated with its negative impact on intelligence. [3] This is because the brain is especially vulnerable to intoxication and poisoning and lead poisoning affects the brain much the same way drug abuse does. [4] Exposed persons experience a suppressed immune system, which leads to a myriad of problems. [5] Increased blood pressure is also a common effect. [6]

Lead Exposure and Children

There is no question that lead exposure negatively impacts the health of children. This is even true for tiny amounts, no safe levels of lead for children have been identified. In children, affected areas include the nervous system and this results in in learning and behavior problems; seizures, coma, and death may also result. In the United States, the most common source of lead exposure for children is lead based paint dust but incidents of exposure by way of low quality toys and trinkets also seems to pop up on an almost regular basis. [7]

Lead poisoning is a huge concern for pregnant women. Chronic, low-level exposure can accumulate in the bones and remain immobile until pregnancy occurs and calcium demands are increased. This can “dislodge” lead deposits into the blood stream and allow them to harm pregnant women and be extremely detrimental to the developing fetus. This lead exposure “time bomb” makes prediction very difficult. [8]

Living or working in areas more susceptible to lead contamination presents a two fold problem. High levels of lead in the environment cause a low and slow chronic exposure to lead that can hinder brain development in children. If children have parents or guardians whose occupations including lead dust, studies have shown that these kids are susceptible to “second hand” exposure through their parents clothing. Dust carried in on clothing is a source of contamination for the home, which further affects children in the home. [9] [10]

In May 2012, the CDC implemented new reference standards for determining childhood lead poisoning. Threshold levels have been reduced, which is expected to initiate an increase in incidences of lead poisoning. [11]

On the international front, the rapid economic development and mineral processing in China has caused a serious lead pollution problem. A large amount of lead has been released into the environment and impacted water, soil, and farming efforts. The blood lead levels of children in China are significantly higher than other developed countries. [12]

Efforts to Reduce Lead Exposure

In the 1970s we started to see lead concentrations in air, water, and soil begin to decline which resulted in reduced blood lead levels in children. However, that doesn’t mean the problem has gone away, not by a long shot. Children are still at risk for lead exposure, especially if they live in a home built prior to the 1978 ban on lead based paint. It must be understood that simply banning a product that has been in place for decades does not make the problem evaporate! In addition, even though most water utilities are in compliance with the Safe Drinking Water Act Lead and Copper Rule of 1991, lead in water remains a problem in some areas. Public water sources should always be monitored for potential contamination. [13] According to Parents for Nontoxic Alternatives, lead is the most prevalent toxin found in water in schools in the United States. They assert there is a need to reevaluate this largely overlooked exposure source to better address childhood lead poisoning. [14]

Purdue University’s Department of Earth Sciences warns that even though significant progress has been made to understand and reduce the risks of lead exposure, cases of poisoning are still unacceptably high in many areas, especially urban areas. Research has indicated the probable reason for this is due to the presence of lead (likely from old paint dust) in soil. They advise that when construction products are undertaken, a process known as “capping” the lead contaminated soil with lead-free soil is a simple, effective method that helps reduce incidences of lead exposure. [15]

References (15)

  1. Flora G, Gupta D, Tiwari A. Toxicity of lead: A review with recent updates. Interdiscip Toxicol. 2012 Jun;5(2):47-58. doi: 10.2478/v10102-012-0009-2.
  2. Karrari P, Mehrpour O, Abdollahi M. A systematic review on status of lead pollution and toxicity in Iran; Guidance for preventive measures. Daru. 2012;20(1):2. doi: 10.1186/1560-8115-20-2. Epub 2012 Jul 19.
  3. Iglesias V, Steenland K, Maisonet M, Pino P. Exposure to lead from a storage site associated with intellectual impairment in Chilean children living nearby. Int J Occup Environ Health. 2011 Oct-Dec;17(4):314-21.
  4. Manto M. Toxic agents causing cerebellar ataxias. Handb Clin Neurol. 2012;103:201-13. doi: 10.1016/B978-0-444-51892-7.00012-7. Review.
  5. García-Lestón J, Roma-Torres J, Mayan O, Schroecksnadel S, Fuchs D, Moreira AO, Pásaro E, Méndez J, Teixeira JP, Laffon B. Assessment of immunotoxicity parameters in individuals occupationally exposed to lead. J Toxicol Environ Health A. 2012;75(13-15):807-18. doi: 10.1080/15287394.2012.690327.
  6. Zeqiri N, Zeqiri S, Skenderaj S. Blood pressure evaluation at the workers exposed to lead. Med Arh. 2012;66(2):92-3.
  7. Centers for Disease Control and Prevention (CDC). Lead poisoning of a child associated with use of a Cambodian Amulet — New York City, 2009. MMWR Morb Mortal Wkly Rep. 2011 Jan 28;60(3):69-71.
  8. Vigeh M, Saito H, Sawada S. Lead exposure in female workers who are pregnant or of childbearing age. Ind Health. 2011;49(2):255-61. Epub 2010 Dec 16.
  9. Khan DA, Qayyum S, Saleem S, Ansari WM, Khan FA. Lead exposure and its adverse health effects among occupational worker’s children. Toxicol Ind Health. 2010 Sep;26(8):497-504. doi: 10.1177/0748233710373085. Epub 2010 Jun 10.
  10. Howarth D. Lead exposure–implications for general practice. Aust Fam Physician. 2012 May;41(5):311-5.
  11. Handler P, Brabander D. Increased incidence and altered risk demographics of childhood lead poisoning: predicting the impacts of the CDC’s 5 µg/dL reference value in Massachusetts (USA). Int J Environ Res Public Health. 2012 Oct 30;9(11):3934-42. doi: 10.3390/ijerph9113934.
  12. Luo W, Ruan D, Yan C, Yin S, Chen J. Effects of chronic lead exposure on functions of nervous system in Chinese children and developmental rats. Neurotoxicology. 2012 Aug;33(4):862-71. doi: 10.1016/j.neuro.2012.03.008. Epub 2012 Apr 6.
  13. Brown MJ, Margolis S. Lead in drinking water and human blood lead levels in the United States. MMWR Surveill Summ. 2012 Aug 10;61 Suppl:1-9. Review.
  14. Lambrinidou Y, Triantafyllidou S, Edwards M. Failing our children: lead in U.S. school drinking water. New Solut. 2010;20(1):25-47. doi: 10.2190/NS.022010eov.
  15. Filippelli GM, Laidlaw MA. The elephant in the playground: confronting lead-contaminated soils as an important source of lead burdens to urban populations. Perspect Biol Med. 2010 Winter;53(1):31-45. doi: 10.1353/pbm.0.0136.

The post Toxic Metal: The Health Dangers of Lead appeared first on The Sleuth Journal.


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