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Colloidal Silver: Risk Without Benefit (Quackwatch)

Saturday, July 14, 2012 18:50
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This article was published a number of years ago and seems to present a reasonable discussion about colloidal silver, its safety and efficacy. The sad truth is that this kind of mis-information is designed to convince the reader that colloidal silver is dangerous. Nothing could be further from the truth, unless you own a Pharmaceutical company.

Stephen Barrett, M.D.

Colloidal silver is a suspension of submicroscopic metallic silver particles in a colloidal base. Long-term use of silver preparations can lead to argyria, a condition in which silver salts deposit in the skin, eyes, and internal organs, and the skin turns ashen-gray. Many cases of argyria occurred during the pre-antibiotic era when silver was a common ingredient in nosedrops. When the cause became apparent, doctors stopped recommending their use, and reputable manufacturers stopped producing them. The official drug guidebooks (United States Pharmacopeia and National Formulary) have not listed colloidal silver products since 1975.

Reply; Colloidal silver manufacturing techniques have evolved to produce nano-sized silver particles which do not product argyria. Large particle colloidal silver stopped being manufactured commercially in the early 1970’s so this statement is irrelevant today.

Dubious Ads

In recent years, silver-containing products have been marketed with unsubstantiated claims that they are effective against AIDS, cancer, infectious diseases, parasites, chronic fatigue, acne, warts, hemorrhoids, enlarged prostate, and many other diseases and conditions. Some marketers claim that colloidal silver is effective against hundreds of diseases.

During 1997 and 1998, Changes International, a Florida-based multilevel company, stated:

Our colloidal silver contains 99.99% pure silver particles suspended indefinitely in demineralized water that kills bacteria and viruses. It can be applied topically and/or absorbed into the blood stream sub-lingually (under the tongue), thereby avoiding the negative effects of traditional antibiotics that kill good bacteria in the lower digestive tract.

An all natural antibiotic alternative in the purest form available. The presence of colloidal silver near a virus, fungi, bacterium or any other single celled pathogen disables its oxygen-metabolism enzyme, its chemical lung, so to say. The pathogens suffocates and dies, and is cleared out of the body by the immune, lymphatic and elimination systems.

Unlike pharmaceutical antibiotics which destroy beneficial enzymes, colloidal silver leaves these beneficial enzymes intact. Thus colloidal silver is absolutely safe for humans, reptiles, plants and all multi-celled living matter.

It is impossible for single-celled germs to mutate into silver-resistant forms, as happens with conventional antibiotics. Also, colloidal silver cannot interact or interfere with other medicines being taken. Colloidal silver is truly a safe, natural remedy for many of mankind’s ills. Colloidal silver can be taken indefinitely because the body does not develop a tolerance to it [1].

Reply; What individuals say about colloidal silver on the Internet or anywhere else is also irrelevant to this discussion. It is interesting to note that hundreds of prominent Universities across America actually AGREE with most of the claims here as a result of intense independent lab tests.

Seasilver International, a California-based multilevel company, had claimed that American are suffering from “silver deficiency.” Although silver is not an essential nutrient, product information posted on the company’s Web site several years ago stated:

The depletion of minerals in our soil has left us deficient of silver, one of our most essential trace minerals, causing a drastic increase in immune system disorders in our society in the last decade. Research has taught us that all disease is allowed to manifest itself because of a weakened immune system. In over 20 years of worldwide research on Colloidal Silver, numerous interviews with government agencies, health care practitioners and their patients, no other nutrient, herb or drug (prescription or over-the-counter) is as safe and effective against all known forms of unfriendly virus, bacteria, and fungus. Additionally, while it is generally known that most antibiotics kill only perhaps 6 or 7 different disease organisms, reports have shown that Colloidal Silver has been used successfully in the treatment of over 650 diseases! Furthermore, strains of disease organisms fail to develop in the presence of Colloidal Silver. Colloidal Silver’s greatest attribute is its unique ability to function as a superior second immune system in the body! [2]

Reply; The claim of 650 disease being cured came from a study conducted at UCLA in California that proved that colloidal silver is highly effective.

Critical Studies and Case Reports

In 1995, an herbal distributor named Leslie Taylor tested nine commonly marketed colloidal silver products available at health-food stores and concluded:

  • Two of the products were contaminated with microorganisms.
  • The amount of silver suspended in solution varied from product to product and would gradually decrease over time.
  • Only five products actually showed antibacterial activity in a laboratory test. To perform the test, she prepared a culture plate with Staphylococcus aureas bacteria, which can cause infections in humans. She then placed a drop from each product on the plate and used disks of two common antibiotics as controls. After eight hours of incubation, she found that bacterial growth had been inhibited around the antibiotics and four of the products.

Of course, the fact that a product inhibits bacteria in a laboratory culture doesn’t mean it is effective (or safe) in the human body. In fact, products that kill bacteria in the laboratory would be more likely to cause argyria because they contain more silver ions that are free to deposit in the user’s skin.

Reply; Who is this investigator and how is any of this information substantiated? No proof here.

FDA laboratory studies have found that the amount of silver in some product samples has varied from 15.2% to 124% of the amount listed on the product labels. The amount of silver required to produce argyria is unknown.

Reply; NutraSilver is tested in FDA-certified labs to be 3,600 PPM without any contaminants. It is not possible to comment on every colloidal silver mistake made.

However, the FDA has concluded that the risk of using silver products exceeds any unsubstantiated benefit [3]. So far, eleven cases of argyria related to silver products have been reported:

  • A 56-year-old man who had sold and used colloidal silver for three years, developed blue/gray discoloration of his fingernails accompanied by a very high blood level of silver [4].

Reply; It is NOT POSSIBLE to get argyria after only three years of use unless this person added large amounts of salt or chlorides to make their own colloidal silver.

  • A married couple who had three years of daily consumption of a drink prepared by administering an electrolytic charge to a bowl of water that contained a silver bar [5].
  • Another couple had been taking a silver-containing “dietary supplement” prescribed by a naturopath [5].
  • A mentally ill man who had been drinking silver-containing herbal tea for about 10 months [5].
  • Stan Jones, Montana’s Libertarian Party candidate for the U.S. Senate, who reportedly started taking colloidal silver in 1999 for fear that Y2K disruptions might lead to a shortage of antibiotics. He made his own concoction by electrically two silver wires in a glass of water [6].

Reply; Mr. Jones made his own concoction of colloidal silver with salt included. He DID NOT take colloidal silver, he took silver COMPOUNDS which is not colloidal silver.

  • Two men, ages 63 and 76, developed argyria after a year of product use inspired by Internet claims [7].
  • A 16-year-old boy developed blue-gray pigmentation of his entire body after ingesting a silver-containing dietary supplement for a year. The product, packaged so that it was identical to bottled water was touted as a preventive for everyday infections [8].
  • A 58-year-old man who treated a presumed kidney infection with a home-brewed colloidal solution 12 times a day for 4 days developed argyria about 4 weeks later [9].
  • A 38-year-old man developed argyria after ingesting approximately 16 ounces of 450 ppm colloidal silver three times a day for 10 months to treat his arthritis and other conditions. He made the solution with a simple battery-operated chamber that leached silver from pure silver wire. He had obtained the plans from information on the Internet [10]. The photograph to the right shows how his skin color compares to that of normal skin.

Reply; Again, Quackwatch does not present the real facts; these people made their own CS and used salt to product silver COMPOUNDS, not colloidal silver.


Enforcement Actions

Between October 1993 and September 1994, the FDA issued warning letters to five colloidal silver marketers:

  • Higher Education Library Publications (H.E.L.P.), of Springfield, Utah, was ordered to stop claiming that its colloidal silver product was effective as a natural antibiotic and might be effective against cancer, genito-urinary diseases, tuberculosis, and AIDS.
  • Nutrition, Inc., of Arvada, Colorado, was ordered to stop stating or implying that its Silvicidal, when administered orally or intravenously, was nontoxic, FDA-approved, and was a broad-spectrum antibiotic that killed bacteria and all virus and fungal infections. In addition, it was falsely claimed to be effective against a long list of specific diseases.
  • Reseau International of Cincinnati, Ohio was ordered to stop claiming that its colloidal silver product was a “natural antibiotic and anti-inflammatory immune system stimulant” and that it was effective against cancer, staph, strep, influenza, general body infections, inflammation, impaired immune system, fungus toxicity, tonsillitis, Meniere’s symptoms, whooping cough, shingles, syphilis, cholera, and malaria. The labeling also stated that colloidal silver could cause major growth stimulation of human tissues and can regenerate
  • Silverado Inc., of Bountiful, Utah, was warned to stop making false claims that its colloidal silver product was effective as an antibiotic, anti-inflammatory, anti-viral, and anti-fungal agent and that it could stimulate the immune system.
  • Unic, of Carmichael, California, was ordered to stop claiming that its colloidal silver product was effective against many diseases and could heal burn-damaged tissue without scarring.

Reply; let’s get real clear here; the objections of the FDA are completely centered on the words used to inform the public about the real benefits of CS, not colloidal silver. Colloidal silver manufactures are prohibited by FDA regulations from making any claims whatsoever, even if they are true and irrefutable.

In October 1996, the FDA proposed to ban the use of colloidal silver or silver salts in over-the-counter products [11].

Reply; Again Quackwatch gets their facts totally wrong. CAN YOU GO TO A Health Food store and buy colloidal silver today? Yes, of course! So how is it that QW says colloidal silver is banned?

A Final Rule banning such use was issued on August 17, 1999 and became effective September 16th. The rule applies to any nonprescription colloidal silver or silver salt product claimed to be effective in preventing or treating any disease [12]. Silver products can still be sold as “dietary supplements” provided that no health claims are made for them. During 2000, the FDA issued warnings to more than 20 companies whose Web sites were making illegal therapeutic claims for colloidal silver products.

In 2000, the Federal Court of Australia banned Vital Earth Company Pty Limited and its director Darryl John Jones from falsely representing that the colloidal silver produced by their “Vital Silver 3000 Zapper,” “Vital Silver 2000 Automatic” and “Vital Silver 2000″:

  • Can kill all disease-causing bacteria, fungi and virus within six minutes of contact
  • Has no harmful side effects; that colloidal silver could be used as an antibiotic for all the acquired diseases of active AIDS
  • Is effective with more than 650 different pathogenic bacteria and virus types
  • Has been used successfully against diseases including AIDS, cholera, diabetes, leprosy, leukemia, lupus, skin cancer, syphilis and whooping cough.

The company was also ordered to pay AUS$9000 in costs and to provide refunds [13].

In 2001, the FTC obtained consent agreements with two companies:

  • Robert C. Spencer and Lisa M. Spencer, doing business as Aaron Company (Palm Bay, Florida). Colloidal silver has been medically proven to kill over 650 disease-causing organisms in the body and is effective in curing diseases ranging from cancer and multiple sclerosis to HIV/AIDS [14].
  • ForMor, Inc., doing business as ForMor International, and its president, Stan Gross (Birmingham, Alabama) agreed not to make unsubstantiated claims that colloidal silver is effective in treating over 650 infectious diseases, has no adverse side effects, and is effective against arthritis, blood poisoning, cancer, cholera, diphtheria, diabetes, dysentery, gonorrhea, herpes, influenza, leprosy, lupus, malaria, meningitis, rheumatism, shingles, staph infections, strep infections, syphilis, tuberculosis, whooping cough, and yeast infections [14].

In 2002, the FTC obtained a consent agreement with Kris Pletschke, doing business as Raw Health, agreed to stop making unsubstantiated claims that its colloidal silver product could treat or cure 650 different diseases; eliminate all pathogens in the human body in six minutes or less; and is medically proven to kill every destructive bacterial, viral, and fungal organism in the body, including anthrax, Ebola, Hanta, and flesh-eating bacteria [15].

In 2002, the Australian Therapeutic Goods Administration amended its rules so that water-treatment products containing substances like colloidal silver for which therapeutic claims are made must meet the requirements of medicines included in the Australian Register of Therapeutic Goods. This means that such products can no longer be legally marketed without proof that they are safe and effective for their intended purpose. The amendment was based on clnclusions that:

  • There is little evidence to support therapeutic claims made for colloidal silver products;
  • The risk to consumers of silver toxicity outweighs the value of trying an unsubstantiated treatment, and bacterial resistance to silver can occur
  • Efforts should be made to curb the illegal availability of colloidal silver products, which is a significant public health issue [16].

Reply; All of these mentions center around what people can say, not about colloidal silver is or how it performs. If you wish to see the truth about colloidal silver in FDA-certified independent lab test, demonstrate that NutraSilver kills pathogens in-vitro quickly, safely and without the horrible side effects of mico-toxins (antibiotics).

The argument is weak, unsubstantiated and designed specifically to to support the Pharmaceutical companies efforts to convince you to use their antibiotics instead of a harmless, benign natural mineral


  1. Product brochure. Changes International, 1997. Downloaded in 1998.
  2. Seasilver International Product Information, accessed October 12, 1998.
  3. Fung MC, Bowen DL. Silver products for medical indications: risk-benefit assessment. Journal of Toxicology and Clinical Toxicology 34:119-26, 1996.
  4. Gulbranson SH and others. Argyria following the use of dietary supplements containing colloidal silver protein. Cutis 66:373-374, 2000.
  5. Hori K and others. Believe it or not—Silver still poisons! Veterinary and Human Toxicology 44(5):291-292, 2002.
  6. Blue Is the color of my candidate’s skin. Associated Press, Oct 2, 2002
  7. Cohen LE and others. Effects of Internet quackery: Argyria in the silver state. Federal Practitioner 21(4):9-17, 2004.
  8. Wickless SC, Schwader TA. Medical mystery—The answer. New England Journal of Medicine 352:2349-2350, 2004.
  9. Brandt D. Argyia secondary to ingestion of homemade silver solition. Journal of the American Academy of Dermatology 53:S105-107, 2005.
  10. Wadhera A, Fung M. Systemic argyria associated with ingestion of colloidal silver. Dermatology Online Journal 11(1):12, 2005.
  11. Federal Register 61:53685-53688, 1996. (To access this document, search the 1996 volume for “colloidal silver.”)
  12. FDA. Final rule: Over-the-counter drug products containing colloidal silver ingredients or silver salts. Federal Register 64:44653-44658, 1999. Download PDF version
  13. Refunds for buyers of alternative therapy devices. News release, Australian Competition and Consumer Commission, May 5, 2000.
  14. “Operation Cure.All” wages new battle in ongoing war against Internet health fraud. FTC news release, June 14, 2001.
  15. FTC announces first two enforcement actions against purveyors of bioterrorism defense products. FTC news release, Feb 27, 2002.
  16. Regulation of colloidal silver and related products. Therapeutic Goods Administration Web site, Aug 19, 2003.

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Total 14 comments
  • Anonymous

    Used COLLOIDAL SILVER for years. Never felt better in my life. Going on 15 now and knew about the stuff before it was popular. Never had any major illness but i did have a deadly car accident where i almost died. Was secretly fed a ruffi drug in my drink at a club in Miami Beach and had a bad accident. Now that kind of pill, you don’t want. Couldn’t prove it to the authorities though. They still have the mind set that cars are good for the quality of the air. Anyway much better now and still taking my colloidal silver. I did catch the flu bug once on the beach but I chalked that up to the influx of illegal Latin aliens that come in over the border and on our airline service into MIA. You don’t know until you see where some of these people come from. I met a couple once from the inland area of the amazon in Brazil. And they talk about the snowbirds. COLLOIDAL SILVER IS A LIFE SAVER TO ME. When I felt wierd or saw something strange on my skin, I took extra doses. I even put some in my eyes when I got pink eye from those swipe machines in Walgreens. Worked on the infection in one day. Don’t believe this article or your doctor. Never turned blue….In fact my skin got ever better looking. Someone should put this into a hand cream like jergens. Would make a fortune and prove the skeptics wrong. But nnnnnoooooo….they want all of you on their own brand of medicine. THE TYPE THAT KILLS YOU AND PROMOTES SYMPTOMS OF ILLNESS.

  • Betsy

    I too have used colloidal silver for many years and no blueness here. They love confusing colloidal silver with other silver concentrations, the beauty of colloidal silver is the molecules are so tiny but effective which is why people using it don’t turn blue. The operative word is “effective”, this is the part that scares them. People not needing to use those toxins they sell that could cause serious side effects to get themselves well.

  • Anonymous

    Despite the first part of this article, these are the facts. Colloidal silver is colloidal silver is colloidal silver and does nothing but rid your wallet of excess cash.

  • Danser

    anonymous and ignorance go hand in hand…..

  • Anonymous

    I am not ignorant. I’m actually very well educated. Of course, you’ll now attack me on my knowledge base because it’s “from the system” lol. I fully recognize the antimicrobial properties of silver and it has GREAT uses for certain applications, usually topical. That said, colloidal silver ain’t some “silver bullet.”

  • Pix

    Colloidal silver is only dangerous if you drink too much of it. First sign of over consumption is you’ll go blue. lolz

  • Danser

    Pix, how many blue people do you know? Argyria is a thing of the past. In order for science to continue this lie, they drag up incidences from 30 years ago. Modern CS does not cause argyria.

  • James Smith

    Rip-off pharmaceutical company’s panties are in a bunch over their bogus antibiotics and their colloidal silver fraudulent lies that aren’t peer reviewed. Anyone who tells you colloidal silver is bad for you is a paid-off liar, well theirs another possibility that they’re just plain stupid. Just because someone has MD after their name doesn’t mean they’re intelligent and I have found that in fact they’re compartmentalized uninformed idiots.

  • Danser

    Which colloidal silver fraudulent lies would you care to reveal here?

  • Danser

    Thank you for your well thought out facts describing your deep insights and revealing your true intellect.

  • Anonymous

    Just another shameless plug for homeopathic garbage. Save your money, IT DOES NOT WORK.

  • Danser

    Yet another display of super-intellect. Amazing, truely.

  • Anonymous

    Yes, “truely” lol. Tell us all about your extensive qualifications “danser.” Apparently you’re not qualified to write in proper English, nor are you adept enough to right-click when there’s a squiggly line. Dude, this site AUTOMATICALLY SPELL CHECKS and you still CANNOT get it right!

  • KNOW

    Completely cured a tooth that needed a root canal using colloidal silver for 2 weeks :-P

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