Vitamin B2 and short-chain acyl-CoA dehydrogenase deficiency

Home of Kyle J. Norton for The Better of Living & Living Health Vitamin B2 (Riboflavin) is one of the member of vitamin B complex found abundantly in Venison, Yogurt, Soybeans, Milk,Mushrooms, Spinach, Tempeh etc.. It plays an important role in converting foods (fats, ketone bodies, carbohydrates, and proteins) to energy.

B. Vitamin B2 (Riboflavin)
Vitamin B2 and short-chain acyl-CoA dehydrogenase deficiency
Short-chain acyl-CoA dehydrogenase deficiency (SCADD) is an inborn error, biochemically characterized by increased plasma butyrylcarnitine (C4-C) concentration and increased ethylmalonic acid (EMA) excretion and caused by rare mutations and/or common gene variants in the SCAD encoding gene. researchers at the University of Amsterdam, Amsterdam, showed that Riboflavin treatment resulted in a decrease in EMA excretion in the mut/var group and in a subjective clinical improvement in four patients from this group. However, this improvement persisted after stopping treatment. These results indicate that high-dose riboflavin treatment may improve the biochemical features of SCADD, at least in patients with a mut/var genotype and low FAD levels(27).

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Sources
(27) http://www.ncbi.nlm.nih.gov/pubmed/19952864

http://medicaladvisorjournals.blogspot.com