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Hepatoprotective role of vitamin B(12) and folic acid

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Home of Kyle J. Norton for The Better of Living & Living Health The vitamin B-complex are essential water-soluble vitamins, including vitamin B1(thiamine), vitamin B2 (riboflavin ), vitamin B3 (niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), biotin, folic acid and vitamin B12 (cobalamins).
Vitamin B12 (Cobalamins) not only plays an important role in fatty acid synthesis and energy production, but also is essential in the normal functioning of the brain and nervous system, and for the formation of blood.
Hepatoprotective role of vitamin B(12) and folic acid
In the study to evaluate the protective role of vitamin B(12) with folic acid against arsenic-induced hepatotoxicity in female rats. Ingestion of sodium-arsenite- contaminated water [0.4 ppm/100 g body weight (b.w.)/day], found that in combination with vitamin B(12) plus folic acid (0.07 and 4.0 μg, respectively/100 g b.w./day) for 24 days to Wistar rats offered a significant protection against alone arsenic-induced distorted liver function, damaged histoarchitecture, elevated oxidative stress, and DNA fragmentation of hepatic tissues(16).
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Sources
(16) http://www.ncbi.nlm.nih.gov/pubmed/21848401

http://medicaladvisorjournals.blogspot.com


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