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Depression is predictable???

Thursday, November 1, 2012 23:53

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Article from University of Oslo

Why are some people more vulnerable to depression than others? The short variant of a gene combined with stressful events may trigger a depressive episode.

By: Svein Harald Milde

Researchers have for a long time tried to understand how a particular gene affects our brain. It is known that the gene, which codes for the neurotransmitter serotonin, predisposes for depression.

When people with the short “serotonin gene” experience stressful events the chances for development of clinical depression increase.PhD candidate Rune Jonassen at the Department of Psychology, University of Oslo has studied the interaction between inheritance and environment.

He has looked into how people with the short variant of this gene reacted to tasks which became progressively more and more difficult. He found that they had difficulties keeping track of their sensory impressions.

“Compare this with stressful episodes in your life; when your life becomes harder and you are exposed to more and more stress. How will your brain react to this?” asks Jonassen.

“People with the short gene had problems with working memory during the tasks we gave them. They were healthy people, but they carry a vulnerability gene”, he says.

As the research subjects solved the tasks their brains where photographed. On the pictures of brain activity Jonassen saw that people with the short gene used greater resources within their brains without doing any better on the tests.

“We saw that they used more energy in the brain structures at the front of the brain linked with task solving. Simultaneously, they made more mistakes on the tasks. The brain stressed and used a lot of energy without the research subjects doing any better. They actually performed poorer on the tasks. “ FOR MORE GOTO http://brightsidebincheck.blogspot.ie/2012/11/depression-is-predictable.html?spref=fb

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