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Tofu Vindaloo and The Main Ingredients Health Benefits

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Home of Kyle J. Norton for The Better of Living & Living Health I. The recipe

Recipe by By: sidnam , posted in All Recipes.com (Source)
Prep Time:
25 Min
Cook Time:
35 Min
Ready In:
1 Hr

Ingredients

  • 3 tablespoons vegetable oil
  • 2 inch piece fresh ginger root, peeled and minced
  • 2 onions, halved and sliced
  • 1/2 head cauliflower, cut into florets
  • 3 carrots, peeled and sliced
  • 3 tablespoons vindaloo curry powder
  • 6 tablespoons tomato paste
  • 1 (15 ounce) can coconut milk
  • 1 cup vegetable broth
  • 1 (15 ounce) can garbanzo beans (chickpeas), drained and rinsed
  • 1 pound extra-firm tofu, cut into 1-inch cubes
  • 1 cup mushrooms, sliced
  • salt to taste

Directions

  1. Heat the vegetable oil in a Dutch oven or large pot over medium-high heat. Stir in the ginger, and cook until fragrant and beginning to brown, about 2 minutes. Stir in the onions, cauliflower, and carrots. Cook and stir until the vegetables have softened, about 5 minutes.
  2. Stir in the vindaloo powder and tomato paste until no lumps of tomato paste remain. Stir in the coconut milk, vegetable broth, and garbanzo beans. Gently fold in the tofu and mushrooms, and season to taste with salt. Bring to a simmer, then reduce heat to medium-low, cover, and simmer until the vegetables are tender, about 15 minutes. Stir occasionally as the vindaloo cooks.

II. The Main Ingredients Health Benefits
II.A. Tofu
Tofu or bean curd is soft white blocks made by coagulating soy milk with substance such as salt or acid or enzyne, a stable emulsion of oil, water, and protein that can be made into tofu, originated from Chinese and part of East and Southeast Asian. Since it is proven to be one of many healthy foods, it become synonymous with vegetarianism and others.

Nutrients
1. Protein
2. Carbohydrate
3. Omega 3 fatty acid
4. Vitamin A
5. B vitamin
6. Magnesium
7. Sodium
8. Manganese
9. Selenium
10. Copper
11. Phosphorus
12. Calcium
13. Potassium
14. Iron
15. Isoflavones
16. Etc.

Health benefits
A. Health benefits according to studies
1. Hair loss
In the orally administered soymetide-4 (MITL), an immunostimulating peptide derived from soybean beta-conglycinin alpha’ and it effect on hair loss found that PGE2, which is produced after activation of COX by soymetide-4, might suppress apoptosis of hair matrix cells and etoposide-induced alopecia by activating NF-kappaB, according to “Anti-alopecia mechanisms of soymetide-4, an immunostimulating peptide derived from soy beta-conglycinin” by Tsuruki T, Takahata K, Yoshikawa M.(a)

b. Metabolic syndrome
In the
assessment of the effect of low daily intake of soybeans in oxidative stress and it effects on the metabolic syndrome (MS) found that Low intake of soy protein for 90 days, besides being well tolerated by the patients, was able to improve several parameters related to the pathophysiology of MS, according to the study of “[Evaluation of the intake of a low daily amount of soybeans in oxidative stress, lipid and inflammatory profile, and insulin resistance in patients with metabolic syndrome].[Article in Portuguese] by Bahls LD, Venturini D, Scripes Nde A, Lozovoy MA, Simão TN, Simão AN, Dichi I, Morimoto HK.(b)

3. Cancer prevention
In the evaluation of Soy isoflavones and it effects on cancers found that Soy isoflavones, linked to reduced cancer risk in Asian epidemiology, may suppress cox-2 induction by activating ERbeta. In aggregate, these considerations suggest that a comprehensive lifestyle strategy targeting cox-2 expression and bioactivity may have tremendous potential for cancer prevention, according to “Minimizing the cancer-promotional activity of cox-2 as a central strategy in cancer prevention” by McCarty MF.(c)

4. Lung cancer
In the Comparison to lung tumor nodules treated with soy isoflavones or radiation, lung tissues from mice found that Soy isoflavones augment destruction of A549 lung tumor nodules by radiation, and also mitigate vascular damage, inflammation and fibrosis caused by radiation injury to normal lung tissue. Soy could be used as a non-toxic complementary approach to improve RT in NSCLC., according to “Soy isoflavones radiosensitize lung cancer while mitigating normal tissue injury” by Hillman GG, Singh-Gupta V, Runyan L, Yunker CK, Rakowski JT, Sarkar FH, Miller S, Gadgeel SM, Sethi S, Joiner MC, Konski AA.(d)

5. Body weight and glycemic control
In the investigation of
Soy isoflavones and it affects on plasma lipids, body weight, and insulin action, found that glucose tolerance tests in adult females were not significantly different with diet, but offspring eating TAD soy had increased glucose disappearance with overall lower glucose and insulin responses to the glucose challenge compared with typical American diet (TAD) casein, according to “Effects of soy vs. casein protein on body weight and glycemic control in female monkeys and their offspring” by Wagner JD, Jorgensen MJ, Cline JM, Lees CJ, Franke AA, Zhang L, Ayers MR, Schultz C, Kaplan JR.(e)

6. Etc.

B. Health Benefits according to the concentration
1.
Tryptophan

Tryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of “The effects of tryptophan depletion on neural responses to emotional words in remitted depression” by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(1)

2. Manganese
It is one of important trace in preventing osteoporosis, according to the study of “[Study of estrogen deficiency impact on manganese levels in teeth and mandible of rats after ovariectomy]. [Article in Polish]” by Rahnama M, Błoniarz J, Zareba S, Swiatkowski W.(1)and regulating blood sugar level, according to the study of “[An inadequate intake of manganese may favour insulin resistance in girls]. [Article in Spanish]” by Rodríguez-Rodríguez E, Bermejo LM, López-Sobaler AM, Ortega RM.(2)

3. Iron
Iron beside is important in enhance the oxygen absorption ti nourish the cells and organs in the body but also form a vital role in the effect of Erythropoietic Stimulating Agents (ESA) hyporesponsiveness, according to “Effects of Iron Supplementation on Erythropoietic Response in Patients with Cancer-Associated Anemia Treated by Means of Erythropoietic Stimulating Agents” by Karlsson T.(3)

4. Protein
In the evaluation of soy protein diet abd it effects on serum creatinine, found that soy feeding was associated with higher renal and hepatic linoleic acid content and higher hepatic alpha-linolenic acid, but lower hepatic arachidonic acid content. and concluded that Isocaloric soy protein feeding ameliorates both epithelial and interstitial changes in the Han:SPRD-cy rat independent of a hypocholesterolemic effect. The histologic benefit is associated with changes in polyunsaturated fatty acid metabolism that may influence both inflammatory and proliferative pathways, according to the study of “Modification of polycystic kidney disease and fatty acid status by soy protein diet” by Ogborn MR, Nitschmann E, Weiler HA, Bankovic-Calic N.(4)


C. Others Health benefit

1. Isoflavones
Isoflavones is one of the most powerful phytoestrogen, which not only helps to reduce symptoms of peri-menopause and menopause due to decreasing of the reproduction of estrogen as aging ( in the evaluation of the effect of red clover isoflavone supplementation over vasomotor and overall menopausal symptoms in postmenopausal women, posted in PubMed(http://www.ncbi.nlm.nih.gov/pubmed/21870906) , researchers found that Red clover isoflavone supplementation was more effective than placebo in reducing daily vasomotor frequency and overall menopausal intensity in postmenopausal women.), it also helps to protect against the development of endometrial carcinoma as well as prolonging the menstrual cycle, ( according to the study of “The effect of phytoestrogens on the female genital tract” by Burton JL, Wells M., posted in PubMed, researchers found that this review will discuss the evidence from both animal studies and humans for an effect of these ubiquitous compounds on the development of the human female genital tract, in addition to prolonging the menstrual cycle, alleviating symptoms of the menopause, and protecting against the development of endometrial carcinoma.

2. Cardiovascular Benefits
Research found that protein of tofu significantly decreases the serum cholesterol by decreasing the levels of bad cholesterol (LDL) but leaving the good cholesterol (HDL) remain the same According to the study of “Effect of soy and milk protein supplementation on serum lipid levels: a randomized controlled trial” by Wofford MR, Rebholz CM, Reynolds K, Chen J, Chen CS, Myers L, Xu J, Jones DW, Whelton PK, He J., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21952693)). It also benefits the cardiovascular health (according to the study of “Soy protein, isoflavones, and cardiovascular health: an American Heart Association Science Advisory for professionals from the Nutrition Committee” by Sacks FM, Lichtenstein A, Van Horn L, Harris W, Kris-Etherton P, Winston M; American Heart Association Nutrition Committee. posted PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16418439)

3. Iron and copper
The ratio of iron and copper is essential to enhance the proper levels of hemoglobin in energy production by transporting and releasing oxygen throughout the body, according to the study of “Influence of copper, iron, zinc and fe (3) (+) haemoglobin levels on the etiopathogenesis of chronic calcific pancreatitis–a study in patients with pancreatitis” by Arumugam G, Padmanaban M, Krishnan D, Panneerselvam S, Rajagopal S., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20809271, researchers found that the results of the present study revealed that the levels of copper and iron, the pro-oxidants and zinc and selenium may influence calcification process in CCP patients. Hypoxia-related tissue injury due to the formation of oxidised haemoglobin may also contribute to the pathogenesis of calcification in pancreas.

4. Superoxide dismutase
Superoxide dismutase are an important antioxidant defense in nearly all cells exposed to oxygen as a class of enzymes that catalyzes the dismutation of free radicals due to existence of copper and Zn in tofu (according to the study of “Cu,Zn-superoxide dismutase gene dosage and cell resistance to oxidative stress: a review” by Peskin AV., posted in Pubmed, researchers found that
There are data that increasing only Cu,Zn-SOD can be toxic, and the balance between Cu,Zn-SOD and peroxide-removing enzymes is supposed to be of prime importance in the antioxidant defence. Role of Cu,Zn-SOD deregulation in carcinogenesis is discussed.

5. Menstrual cramp and pain
The existence of Omega 3 fatty acid reduces the production of prostaglandin hormone, by balancing the ratio of Omega 3 and 6 fatty acids, resulting in lessening the movement of abdominal muscle that cause menstrual cramps and pain , according to the study of “Effect of Clupeonella grimmi (anchovy/kilka) fish oil on dysmenorrhoea” by Moghadamnia AA, Mirhosseini N, Abadi MH, Omranirad A, Omidvar S., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20795425), researchers found that There was also a marked reduction in low back pain and abdominal pain (P
6. Selenium
Selenium is classified as one of antioxidant trace mineral that helps to increase the immune function to fight the forming of free radicals, infection and inflammation caused by oxidation, irregular cells growth, virus and bacteria, etc., according tothe study of “Protective role of intraperitoneally administrated vitamin E and selenium on the levels of total lipid, total cholesterol, and fatty acid composition of muscle and liver tissues in rats” by Yilmaz O, Celik S, Cay M, Naziroğlu M., posted in PubMed, researchers found that the level of total lipid and cholesterol in muscle and liver tissues were reduced by administrating vitamin E and Se together. Additionally, the fatty acid synthesis in the muscle and liver tissues was decreased by this process) and prevent plague accumulated cause of Atherosclerosis (according to the study of ‘Vitamin-mineral supplementation and the progression of atherosclerosis: a meta-analysis of randomized controlled trials” by Bleys J, Miller ER 3rd, Pastor-Barriuso R, Appel LJ, Guallar E., posted in PubMed) thus reducing the risk of heart diseases and hypertension.

7. Etc.

Side effects
1. Over consumption of tofu can cause dementia in older age groups.
2. Allergic effect for some people.
3. Since it contains a measure amount of axalates, it causes problem for people with kidney and gallbladder diseases.

4. Etc.

II.B. Cauliflower 
Cauliflower is the species Brassica oleracea, including cabbage, brussels sprouts, kale and broccoli , belong to the family Brassicaceae, native to Italy.

Nutritional Supplements

Nutrients
1. Carbohydrates
2. Sugars
3. Fiber
4. Omega 3 fatty acid
5. Protein
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (VitaminB3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin. B9)
12. Vitamin C
13. Vitamin K
14. Calcium
15. Iron
16. Magnesium
17. Phosphorus
18. Potassium
19. Tryptophan
20. Zinc
21. Etc.

Health benefits
A. Health benefits according to studies
1. Anti-proliferative activity
In the investigation of regular consumption of fresh and cooked Brassicaceae and its effect in reducing the risk of cancer and heart disease found that Anti-proliferative and chemoprotective effects towards DNA oxidative damage of fresh and cooked vegetable extracts were evaluated by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium and Comet assays on HT-29 human colon carcinoma cells. The fresh vegetable extracts showed the highest anti-proliferative and antioxidant activities on HT-29 cells (broccoli>cauliflower = Brussels sprouts). No genotoxic activity was detected in any of the samples tested. The cooking methods that were applied influenced the anti-proliferative activity of Brassica extracts but did not alter considerably the antioxidant activity presented by the raw vegetables. Raw, microwaved, boiled (except broccoli) and steamed vegetable extracts, at different concentrations, presented a protective antioxidative action comparable with vitamin C (1 mm), according to “Anti-proliferative activity and chemoprotective effects towards DNA oxidative damage of fresh and cooked Brassicaceae” by Ferrarini L, Pellegrini N, Mazzeo T, Miglio C, Galati S, Milano F, Rossi C, Buschini A.(a)

2. Colon cancer
In evaluation of iquid chromatography-electrospray ionization (LC-ESI) mass spectrometry two glucosinolates, glucoiberin and 3-hydroxy,4(α-L-rhamnopyranosyloxy) benzyl glucosinolate of the aqueous extract of Brassica oleraceae L var. italica found that when myrosinase hydrolysate was tested for cytotoxic activity on the colon cancer cell line it showed very high activity – 95% lethality up to 0.78 µg/mL, according to “Myrosinase Hydrolysates of Brassica oleraceae L. Var. italica Reduce the Risk of Colon Cancer” by Hashem FA, Motawea H, El-Shabrawy AE, Shaker K, El-Sherbini S.(b)

3. Antioxidant capacity
In the classification of polyphenols, flavonoids and glucosinolates of vegetables belonging to the Brassicaceae family and theirs antioxidant effects found that the antibacterial activity was determined against Gram-positive and Gram-negative bacteria. York cabbage extract exhibited significantly higher antibacterial activity against Listeria monocytogenes (100%) and Salmonella abony (94.3%), being the most susceptible at a concentration of 2.8%, whereas broccoli, Brussels sprouts and white cabbage had moderate to weak activity against all the test organisms. Good correlation (r2 0.97) was found between total phenolic content obtained by spectrophotometric analysis and the sum of the individual polyphenols monitored by HPLC-DAD, according to “Phenolic composition, antioxidant capacity and antibacterial activity of selected Irish Brassica vegetables” by Jaiswal AK, Rajauria G, Abu-Ghannam N, Gupta S.(c)

4. Anti inflamatory effect
In the research of Benzyl isothiocyanate (BITC) found abundantly in Brassica vegetables and it anti inflammatory effect found that lipopolysaccharide (LPS)-stimulated phosphorylation of extracellular signal regulated kinase (ERK)1/2 and Akt was suppressed by BITC. BITC also inhibited ear edema formation and the protein expression of iNOS and COX-2 in mouse skin treated with TPA. We demonstrate that BITC is a potent anti-inflammatory agent, and the anti-inflammatory properties of BITC may result from the downregulation of NFkappaB signaling, according to “Benzyl isothiocyanate exhibits anti-inflammatory effects in murine macrophages and in mouse skin” by Lee YM, Seon MR, Cho HJ, Kim JS, Park JH.(d)

5. Arthritis
In the observation of 3,3′-Diindolylmethane (DIM), a natural compound formed during the autolysis of glucobrassicin presented in Brassica food plants and its anti-arthritis effect, found that the inhibition of kappa B ligand (RANKL) by DIM. DIM has shown anti-arthritis activity in animal models via inhibiting the expression of RANKL, and thus may offer potential treatments for arthritis and associated disorders, according to “3,3′-Diindolylmethane attenuates experimental arthritis and osteoclastogenesis” by Dong L, Xia S, Gao F, Zhang D, Chen J, Zhang J.(e)

6. Etc.

B. Health benefits according to concentration
1. Vitamin C
In the evaluation of pulmonary dysfunction. and it effects on pulmonary dysfunction found that At present, evidence from randomised-controlled trials is insufficient to recommend a specific role for vitamin C in the treatment of asthma. Further methodologically strong and large-scale randomised controlled trials are needed in order to address the question of the effectiveness of vitamin C in children with asthma but some outcome data showed effectiveness on lung function, symptom scores, IgE levels and inhaled steroid use. One small study showed a significant difference in % drop in FEV1 post-exercise, according to the study of “Vitamin C supplementation for asthma” by Kaur B, Rowe BH, Arnold E.(I)

2. Vitamin K
Vitamin K not only plays an important role in protecting our skin from aging, it is also needed for the proper clotting of blood, thus decreasing the risk of excessive bleeding, in a study of “Delayed vitamin K deficiency as a cause of bleeding: still a concern in the 21st century!” by Kasatkar P, Shetty S, Ghosh K., posted in PubMed, researchers found that Laboratory tests confirmed acquired bleeding diathesis due to vitamin K deficiency, which was corrected after adequate vitamin K supplementation. VKDB is not an uncommon phenomenon and should be considered in the differential diagnosis of a child with bleeding diathesis.

3. Folate
In the investigation of the prevalence and multifactorial etiology of anemia among Indian human immunodeficiency virus (HIV)-infected children and its effect on anemia, found that Anemia, particularly iron deficiency anemia and anemia of inflammation, is highly prevalent among children with HIV infection. Micronutrient supplements (iron and, folate) combined with ART(antiretroviral therapy) improved anemia in HIV-infected children, according to “The prevalence and etiology of anemia among HIV-infected children in India” by Shet A, Arumugam K, Rajagopalan N, Dinakar C, Krishnamurthy S, Mehta S, Shet AS.(II)

4. Vitamin B6
c. 1. Vitamin B6 or Pyridoxine beside is important in enhancing the developing red blood cells by stimulating the production of hemoglobin, it also helps to keep blood sugar levels steady during the process of breaking down stored energy in gestation pregnancy, according to the study of “Improvement of oral glucose tolerance in gestational diabetes by pyridoxine” by Bennink HJ, Schreurs WH., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/1131652)

c.2. It also plays a pivotal role as a methyl donor in the basic cellular process of methylation, through which methyl groups are transferred from one molecule to another, resulting in the formation of a wide variety of precess, including regulation of gene expression, protein function, and RNA metabolism. When levels of B6 are inadequate, it may cause faulty Methylation with high levels of homocysteine that can cause variety of disease, including cervical dysplasia, faulty detoxification and impaired DNA repair, etc., according to the study of “Back To Life Natural Health Center – Healthcare Through Natural Methods“(http://www.backtolifehealth.com/Methylation.htm)

5. Potassium
Potassium beside is important in maintaining the regular contraction and relaxation of the muscle, that helps to reducing the risk of hypokalemia, it also helps the lymphatic system in regulating the levels of fluid in the body, thus lessening the risk of lymphedema, swelling caused by the accumulation of lymph fluid. In a study of “Narrative review: evolving concepts in potassium homeostasis and hypokalemia” by Greenlee M, Wingo CS, McDonough AA, Youn JH, Kone BC., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19414841), researchers found that recent experimental insights into the participation of feedback and feedforward control mechanisms in potassium homeostasis. New data make clear that feedforward homeostatic responses activate when decreased potassium intake is sensed, even when plasma potassium concentration is still within the normal range and before frank hypokalemia ensues, in addition to the classic feedback activation of renal potassium conservation when plasma potassium concentration decreases.

6. Dietary fiber
Daily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of “Efficacy of high-fiber diets in the management of type 2 diabetes mellitus” by Wolfram T, Ismail-Beigi F.(III)

7. Etc.

C. Other health benefits
1. Anti-Tumors
Cauliflower contains high amount of glucosinolates which are potent inducers of protective enzymes that provide defense against cancer-causing chemicals, thus reducing the risk of developing liver, colon, mammary gland, pancreatic tumors, according to the article of “Glucosinolates” by Wikipedia(1)

2. Cancers
The compound indole-3-carbinol has exerted the peoperty in preventing the growth of tumor and cancer, as it may be considered as a potential natural cancer preventive compounds bnecuase of its mechanisms of action, according to the study of “Cancer prevention with natural compounds” Gullett NP, Ruhul Amin AR, Bayraktar S, Pezzuto JM, Shin DM, Khuri FR, Aggarwal BB, Surh YJ, Kucuk O.(2)

3. Antioxidants
Cauliflower improves the immune function in fighting against the forming of free radical due to its high amount of phytonutrients, according to the study of “Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells” Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH(3)

4. Localized adjuvant Arthritis
Cauliflower contains high amount of Vitamin C that plays a role in the production of collagen, an important protein found in bones and joints that helps reduce the risk of infection and inflammation, according to the study of “Vitamin C influence on localized adjuvant arthritis” by
Davis RH, Rosenthal KY, Cesario LR, Rouw GR.(4)

5. Cardiovascular diseases

Omega 3 fatty acid helps to balance the ratio of fatty acid that reduces the risk of bad cholesterol forming of plagues that cause thickening and hardening of arterial wall, causing heart diseases, according to the study of “Omega-3 polyunsaturated fatty acids and cardiovascular diseases” by Lavie CJ, Milani RV, Mehra MR, Ventura HO.(5)

6. Etc.

Side effects
1. Excessive intake of these cauliflower may cause health problems to some people who are susceptible to purine-related problems.
2. Also, purine can cause forming of kidney stone
3. Etc.

III.C. Onions
The onion is a plants in the genus Allium, belongs to the family Alliaceae, a close relation of garlic. It It is often called the “king of vegetables” because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world’s cultures. Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

Nutrients
 1. Carbohydrate
2. Protein
3. Dietary fiber
4. Fat

5. Vitamin A
6. B vitamin
7. Folate
8. Vitamin C
9. Vitamin E
10. Vitamin K
11. Calcium
12. Iron
13. Magnesium
14. Potassium
15. Phosphorus
16. Zinc
17. Sodium
18. Etc.

Health benefits
A. Health benefits according to studies
1. Diabetes
In the investigation of the effect of feeding 15 mg% capsaicin diet or 3% freeze dried onion powder and theirs anti diabetes effects, found that blood cholesterol was lowered significantly by dietary onion in diabetic animals. Cholesterol decrease was exclusively from LDL-VLDL fraction. Significant decrease in blood phospholipids and triglycerides also brought about by dietary onion. Hepatic cholesterol, triglycerides, phospholipids which were elevated under diabetic condition were countered significantly by dietary onion, according to “Influence of dietary capsaicin and onion on the metabolic abnormalities associated with streptozotocin induced diabetes mellitus” by Babu PS, Srinivasan K.(a)

2. Antioxidant and anti-apoptotic effects
In the research of onion (Allium cepa) (ACE) extracts onion (Allium cepa) extracts and theirs antioxidant and anti-apoptotic effects found that the biochemical and histological disturbances were effectively attenuated on pretreatment with ACE. The present study showed that ACE may be a suitable cardioprotector against toxic effects of (DOX) doxorubicin, according to “Antioxidant and anti-apoptotic effects of onion (Allium cepa) extract on doxorubicin-induced cardiotoxicity in rats” by Alpsoy S, Aktas C, Uygur R, Topcu B, Kanter M, Erboga M, Karakaya O, Gedikbasi A.(b)

3. Hypertrophic scars
In the evaluation of topical treatments and management of hypertrophic scars found that topical treatments such as silicone gel sheeting and ointment, onion extract, vitamin E, pressure garment therapy, massage therapy, and topical imiquimod 5% cream in the management of hypertrophic scars, according to study of “Topical modalities for treatment and prevention of postsurgical hypertrophic scars” by Foo CW, Tristani-Firouzi P.(c)

4. Atherosclerosis (AS)
In the investigation of onion extarcts and its efect in on endogenous H2S and adrenomedulin (ADM) and on atherosclerotic progression found that onion extract exerted a marked antiatherogenic effect in association with the up-regulation of the endogenous CSE/H2S pathway but down-regulation of the ADM/CRLR family in rats with atherosclerosis, according to “Effects of Onion Extract on Endogenous Vascular Hydrogen Sulfide and Adrenomedulin in Atherosclerotic Rats” by Li W, Tang C, Jin H, Du J.(4)

5. Etc.

B. Health Benefits according to concentration
1. Vitamin C
In the evaluation of pulmonary dysfunction. and it effects on pulmonary dysfunction found that At present, evidence from randomised-controlled trials is insufficient to recommend a specific role for vitamin C in the treatment of asthma. Further methodologically strong and large-scale randomised controlled trials are needed in order to address the question of the effectiveness of vitamin C in children with asthma but some outcome data showed effectiveness on lung function, symptom scores, IgE levels and inhaled steroid use. One small study showed a significant difference in % drop in FEV1 post-exercise, according to the study of “Vitamin C supplementation for asthma” by Kaur B, Rowe BH, Arnold E.(1)

2. Dietary Fibers
Daily intake of right amount of fibers can prvent and treata. Diabetes, as Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of “Efficacy of high-fiber diets in the management of type 2 diabetes mellitus” by Wolfram T, Ismail-Beigi F.(2)

3. Molybdenum
Molybdenum cofactor is vital for human enzymes, including xanthine oxidase, sulfite oxidase, and aldehyde oxidase, Deficiency may cause
a. Prenatal brain disruption, according to the study of “Prenatal brain disruption in molybdenum cofactor deficiency” by Carmi-Nawi N, Malinger G, Mandel H, Ichida K, Lerman-Sagie T, Lev D.(3)
b. Uniparental isodisomy with microcephaly and developmental delay, according to the study of “Maternal uniparental isodisomy is responsible for serious molybdenum cofactor deficiency” by Gümüş H, Ghesquiere S, Per H, Kondolot M, Ichida K, Poyrazoğlu G, Kumandaş S, Engelen J, Dundar M, Cağlayan AO.(4)

4. Manganese
Manganese beside is a mineral essential for energy production and metabolism of foods, it also helps to improve immune-system functioning that reduces the risk of inflammation, according to the study of “The effects of 3, 4 or 5 amino salicylic acids on manganese-induced neuronal death: ER stress and mitochondrial complexes” by Yoon H, Lee GH, Kim DS, Kim KW, Kim HR, Chae HJ., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21477646 researchers indicated that the salicylate analogues and the antioxidants did not mediate ER stress in this model. The salicylate analogues reduced reactive oxygen species (ROS) and reversed the deficient mitochondrial membrane potential that was induced by Mn. Taken together, the 3, 4, 5 ASA worked in a similar way, regulating the Mn-induced mitochondrial dysfunction and protecting cells.

5. Etc.

C. Other health benefits
1. Iron Deficiency Anemia
Since onion contains a measurable amount of iron, it is one of the natural food that can be beneficial for the treatment of anemia, by enhancing the production of red blood cells, and quantity of hemoglobin in the blood, thus reducing the risk of iron-deficiency anemia.

2. Anticoagulation
Similar to garlic and ginger, onions is best known of anti coagulation by making the blood thinner, thus reducing the risk of heart diseases and prevent the forming of plague building up in arterial wall as a result of lower levels of bad cholesterol, according study of “Inhibition of whole blood platelet-aggregation by compounds in garlic clove extracts and commercial garlic products” by Lawson LD, Ransom DK, Hughes BG., posted in PubMed

3. Anti-inflammatory

Since it contains high amount of antioxidants, onion enhances the immune system in fighting against the forming of free radicals and foreign invasion, thus eeducing the symptoms of inflammatory conditions such as arthritis and gout and infection caused by bacteria, including E.coli and salmonella,etc., according to the study of Antibacterial and antioxidant activities of quercetin oxidation products from yellow onion (Allium cepa) skin.” by Ramos FA, Takaishi Y, Shirotori M, Kawaguchi Y, Tsuchiya K, Shibata H, Higuti T, Tadokoro T, Takeuchi M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19127724)

4. High Blood pressure
Study found that onion helps to reduce high blood pressure due to quercetin, the compound most commonly associated with onions, according to the study of “The antihypertensive effects of quercetin in a salt-sensitive model of hypertension” by Mackraj I, Govender T, Ramesar S., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/18356687)

5. Probiotic
Fructo-oligosaccharides in onion stimulates the growth of good bacteria in the colon according to the study of “A formula containing galacto- and fructo-oligosaccharides prevents intestinal and extra-intestinal infections: an observational study” by Bruzzese E, Volpicelli M, Squeglia V, Bruzzese D, Salvini F, Bisceglia M, Lionetti P, Cinquetti M, Iacono G, Amarri S, Guarino A., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19231042) and help reduce the risk of colcon tumors and cancers, according to the study of “Effects of a 3-mo consumption of short-chain fructo-oligosaccharides on parameters of colorectal carcinogenesis in patients with or without small or large colorectal adenomas” by Boutron-Ruault MC, Marteau P, Lavergne-Slove A, Myara A, Gerhardt MF, Franchisseur C, Bornet F; Eripolyp Study Group., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/16573377)

6. Etc.
Side effect
1. No major side effect is known, but people with ulcer and taking blood thinner medicine should consult their doctor before eating high amount of onion

2. Bad breath, heartburn and stomach uncomfortable may be a concern to some people.
3. Etc.

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For the world most healthy foods lists, visit http://healthy-foods-index.blogspot.com/2011/03/healthy-foods-list.html,
For other health articles, please visit http://medicaladvisorjournals.blogspot.ca

Sources of Onion
(a) http://www.ncbi.nlm.nih.gov/pubmed/9350033
(b) http://www.ncbi.nlm.nih.gov/pubmed/21996788
(c) http://www.ncbi.nlm.nih.gov/pubmed/21856542
(d) http://www.ncbi.nlm.nih.gov/pubmed/21506909

(1) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(2) http://www.ncbi.nlm.nih.gov/pubmed/20713332
(3) http://www.ncbi.nlm.nih.gov/pubmed/21285035
(4) http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8749.2010.03724.x/pdfSources of Cauliflower
(a) http://www.ncbi.nlm.nih.gov/pubmed/22088277
(b) http://www.ncbi.nlm.nih.gov/pubmed/22076869
(c) http://www.ncbi.nlm.nih.gov/pubmed/21941903
(d) http://www.ncbi.nlm.nih.gov/pubmed/19760383
(e) http://www.ncbi.nlm.nih.gov/pubmed/19854159

(I) http://www.ncbi.nlm.nih.gov/pubmed/19160185
(II) http://www.ncbi.nlm.nih.gov/pubmed/22009132
(III) http://www.ncbi.nlm.nih.gov/pubmed/20713332

(1) http://en.wikipedia.org/wiki/Glucosinolate
(2) http://www.ncbi.nlm.nih.gov/pubmed/20709209
(3) http://www.ncbi.nlm.nih.gov/pubmed/17119270
(4) http://www.ncbi.nlm.nih.gov/pubmed/2376830
(5) http://www.ncbi.nlm.nih.gov/pubmed/19660687

Sources of Tofu
(a) http://www.ncbi.nlm.nih.gov/pubmed/15808899
(b) http://www.ncbi.nlm.nih.gov/pubmed/22011856
(c) http://www.ncbi.nlm.nih.gov/pubmed/22001128
(d) http://www.ncbi.nlm.nih.gov/pubmed/22079530
(f) http://www.ncbi.nlm.nih.gov/pubmed/19484707

(1) http://www.ncbi.nlm.nih.gov/pubmed/19539268
(2) http://www.ncbi.nlm.nih.gov/pubmed/22072339
(3) http://www.ncbi.nlm.nih.gov/pubmed/22111015
(4) http://www.millipore.com/references/tech1/7yv3hk http://medicaladvisorjournals.blogspot.com


Source: http://medicaladvisorjournals.blogspot.com/2013/08/tofu-vindaloo-and-main-ingredients.html


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