Severity of symptom flare after moderate exercise is linked to cytokine activity in CFS
White AT, Light AR, Hughen RW, Bateman L, Martins TB, Hill HR, Light KC.Journal Psychophysiology. 2010 Jul 1;47(4):615-24. doi: 10.1111/j.1469-8986.2010.00978.x. Epub 2010 Mar 4.Affiliation
Abstract Chronic fatigue syndrome (CFS) patients often report symptom flare (SF) for >24 h after moderate exercise (post-ex). We hypothesized that SF is linked to increases in circulating cytokines and CD40 Ligand (CD40L). In 19 CFS patients and 17 controls, mental and physical fatigue and pain symptom ratings were obtained together with serum for 11 cytokines and CD40L before and at 0.5, 8, 24, and 48 h post-ex. Before exercise, CFS had lower CD40L (peta, IL-12, IL-6, IL-8, IL-10, and IL-13 (pPMID 20230500 [PubMed - indexed for MEDLINE] http://www.ncbi.nlm.nih.gov/m/pubmed/20230500/
Source: http://niceguidelines.blogspot.com/2014/09/severity-of-symptom-flare-after.html
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