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Squalene Market Insights: Key Trends and Growth Drivers in 2025

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The global squalene market is experiencing significant growth across various sectors, especially in cosmetics, pharmaceuticals, and nutraceuticals. As consumer preferences shift toward more natural, sustainable products, the demand for squalene, a naturally occurring compound found in plants and animals, has surged. This article provides an in-depth analysis of the squalene market, its key applications, sources, and the growth trends in Europe, North America, and globally. In terms of value, the squalene market is estimated to grow from USD 141 million in 2022 to USD 202 million by 2028, at a CAGR of 6.34%. The market research study includes information on market factors such as the market dynamics, drivers, restraints, challenges, threats, potential growth opportunities, squalene market trends, development patterns, financial information, latest technologies, innovations, leading competitors, and regional analysis of the market.

What is Squalene and Why is It Important?

Squalene is a natural organic compound that is primarily used in the cosmetic and pharmaceutical industries due to its ability to moisturize and protect the skin. It is a hydrocarbon that can be sourced from animal liver oil, plants, or biosynthetic processes. Its versatility makes it a key ingredient in anti-aging creams, vaccines, and dietary supplements.

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Global Market Size and Growth

The global squalene market has witnessed impressive growth over the past few years, and this trend is expected to continue in the upcoming years.

⇛ Europe: The European squalene market was valued at USD 44.33 million in 2023 and is projected to grow at a healthy pace, reaching USD 109.77 million by 2032.

⇛ North America: The North American market generated a revenue of USD 29.3 million in 2021 and is expected to reach USD 67.1 million by 2030, growing at a compound annual growth rate (CAGR) of 9.7%.

Globally, squalene is seeing increased adoption due to rising awareness of its benefits, coupled with growing demand for natural ingredients in personal care products and vaccines.

Primary Sources of Squalene

⇏ Animal Sources: Shark liver oil has historically been the primary source of squalene. However, due to sustainability concerns, its use has been increasingly regulated.

⇏ Vegetable Sources: Plant-based sources, including olive oil, palm oil, and amaranth oil, are becoming more popular as consumers demand more sustainable and ethical products.

⇏ Biosynthetic Sources: The advent of biotechnology has led to the development of biosynthetic processes, where squalene is produced using genetically modified yeast, offering a more sustainable alternative.

As sustainability becomes a focal point for manufacturers and consumers, the plant-based and biosynthetic sources of squalene are seeing higher demand.

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Key Applications of Squalene

Squalene is used across several industries for various applications:

⇛ Cosmetics and Personal Care: Squalene is a prized ingredient in skincare formulations due to its moisturizing, anti-aging, and antioxidant properties. It enhances the skin’s elasticity and can help reduce the appearance of fine lines.

⇛ Pharmaceuticals: Squalene plays a vital role in the production of vaccines, particularly as an adjuvant to improve the efficacy of vaccines. It has also been linked to improving immune responses in patients.

⇛ Nutraceuticals: Squalene is gaining popularity in dietary supplements, where it is touted for its potential health benefits, including its antioxidant and anti-inflammatory properties.

These applications are driving demand in both North America and Europe, where squalene is increasingly used in high-end cosmetics and advanced pharmaceutical formulations.

Market Trends in Europe and North America

In Europe and North America, several factors are contributing to the growth of the squalene market:

⇛ Consumer Demand for Natural Ingredients: Consumers are more aware of the benefits of natural ingredients, which is pushing the demand for squalene in cosmetics and personal care products.

⇛ Advancements in Biotechnology: The development of biotechnological processes for producing squalene has made it more accessible and sustainable, thereby reducing reliance on animal-based sources.

⇛ Regulatory Support: In both regions, regulatory agencies are promoting the use of plant-based and biosynthetic squalene, as these sources align better with sustainability goals.

As these factors converge, the squalene market is poised for significant growth, particularly in sectors where sustainability and ethical sourcing are highly valued.

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Challenges in the Squalene Market

Despite the promising growth prospects, the squalene market faces several challenges:

✔️ Sustainability Issues: While plant-based and biosynthetic sources are on the rise, the environmental impact of sourcing squalene from animals, especially sharks, remains a key concern.

✔️ Regulatory Hurdles: As demand for squalene increases, regulatory agencies are tightening rules on its use in pharmaceuticals and cosmetics. This may slow down market growth as companies work to meet these requirements.

✔️ Market Competition: With the rise of biosynthetic squalene, companies that previously relied on animal-based sources may find it difficult to maintain their market share.

However, innovations in production technologies and growing consumer awareness about sustainability are likely to mitigate these challenges over time.

Major Players in the Squalene Market

The squalene market is highly competitive, with numerous key players vying for a share in the growing industry. Notable companies include:

  • Amyris, Inc (US)
  • SOPHIM (France)
  • Merck KGaA (Germany)
  • Kishimoto Special Liver Oil Co., Ltd. (Japan)
  • Empresa Figueirense De Pesca (Portugal)
  • Arbee (India)
  • Cibus (US)
  • Otto Chemie Pvt. Ltd. (India)
  • Arista Industries (US)
  • Oleicfat s.l. (Spain)

These companies are leading the way in the production and supply of squalene from both plant-based and biosynthetic sources. They are investing heavily in research and development to cater to the rising demand for sustainable and high-quality squalene.

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Future Outlook for the Squalene Market

The future of the squalene market looks promising, with several growth drivers:

➥ Sustainable Sourcing: The continued shift towards plant-based and biosynthetic squalene will likely drive market growth, as these sources align with consumer preferences for sustainable products.

➥ Expanding Applications: Beyond cosmetics and pharmaceuticals, squalene is expected to see further expansion in nutraceuticals, biofuels, and other industries.

➥ Technological Advancements: Innovations in biotechnology will make the production of squalene more efficient and cost-effective, further driving its adoption.

The global market for squalene is set to grow exponentially, with both Europe and North America contributing significantly to its success.

Conclusion

The squalene market is witnessing impressive growth, driven by the increasing demand for natural ingredients in cosmetics, pharmaceuticals, and nutraceuticals. As consumer demand for sustainable and ethical products rises, the shift toward plant-based and biosynthetic squalene will continue to shape the market. With advancements in biotechnology and expanding applications, the squalene market is poised for long-term growth across the globe, particularly in Europe and North America. As the industry evolves, stakeholders must focus on sustainable sourcing, innovation, and regulatory compliance to capitalize on the growing demand for this versatile compound. 



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