Not much is known at this point.
Listen as the latest information is released.
Shocking video footage of the carnage shows debris blown across a street as thick smoke fills the skyline.
The blast ripped through a multi-storey building adjoining a nursery in Calle de Toledo this afternoon. Spanish TV channel La Sexta said four people had died, citing government sources.
The building belongs to the Catholic Church, local authorities said.
Massive explosion destroys building in downtown Madrid
Reuters LIVE – Huge Explosion in Madrid Leaves at Least Two Dead
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