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Vaccine Patch Pitched as Safe: Don't Believe It!

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Vaccine patches, the next great vaccination delivery technology, is already being pushed as safe. A journal with the oxymoron name,Nature Medicine, has published a study that claims delivering vaccinations through skin patches with tiny plastic needles is both effective and safe. The safety claim is both premature and demonstrably untrue.

The study, done by researchers at Georgia Institute of Technology and Emory University, used microneedle skin patches with a flu vaccine on mice. The vaccine impregnated needles, made of polyvinyl pyrrolidone (PVP), a mere .625 micrometers long, literally melt into the skin.

Although microneedle patches won’t be available for another two years or so, the hype is already in full gear. It’s obvious in the recent study that resulted in glowing press reports. It throws caution aside and declares microneedles safe—based on only a three-month study of use on mice.

It’s claimed that these patches will increase the efficacy of vaccines, be painless, so easy and convenient that they could be mailed to people for self-application, and of course, they’ll be safe. This last claim is hyperbole of the worst sort.

These facts about PVP were documented by the International Agency for Research on Cancer (IARC)(1):

  • Subcutaneous injections of PVP into mice, rats, and rabbits resulted in sarcomas. Just one implantation of PVP peritoneally can result in multiple local tumors.
  • Intravenous PVP injections into rats were associated with multiple tumors at distant locations in the body…
  • Continued here…



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