Eli Lilly Drug Failure Highlights Fatal Flaw in Modern Medicine
Eli Lilly has stopped the trial of a drug intended for Alzheimer’s patients because it made their condition worse, not to mention causing skin cancer. The question that needs to be asked is how and why Lilly pushed a drug through both first and second stage trials, only to find that it makes the targeted condition worse when tested on real human beings in a stage three trial. Obviously, something significant is being missed by modern medicine’s approach.
Eli Lilly’s Flawed Logic
The drug, semagacestat—also known as LY450139, but we’ll call it Sema for simplicity—was based on the assumption that destroying the plaque found in the brains of Alzheimer’s patients would improve their symptoms. The logic was:
These plaques consist of a protein called amyloid beta.
The amyloid beta protein is formed when an enzyme, gamma secretase, breaks down a larger protein.
A drug that interferes with the action of gamma secretase would prevent the protein’s breakdown into amyloid beta, which forms the plaque found in Alzheimer’s brains.
Alzheimer’s patients would get better, or the progression of their disease would stop or slow.
But Alzheimer’s patients got worse on taking Sema. What’s wrong with the theory? The answer lies at the heart of modern medicine: a fatal flaw.
Modern Medicine’s Flawed Equation
There is an assumption that symptoms equate with disease, and that treating symptoms is the same thing as treating the disease. Nothing could be further from the truth.
Symptoms are the body’s response to disease, not the disease itself. In most cases, they are actually the body’s attempts to heal. Removal of symptoms does not remove disease. Removal of symptoms may ease suffering, and sometimes that’s an appropriate response—as long as it’s understood that alleviation is the goal, rather than healing.
Sadly, modern medicine seems to believe that symptom alleviation is the goal. That’s why it will treat fever as the disease. However, it isn’t; it’s a healing response to disease. Fever reduction interferes with healing, allowing the proliferation of harmful conditions, such as infections and tumors. Yet, fever reduction is often the primary goal of modern medicine’s treatment.
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