Isolated adrenocorticotropic hormone deficiency presenting with hypercalcemia in a patient on long-term hemodialysis
Home of Kyle J. Norton for The Better of Living & Living Health Adrenocorticotropic hormone (ACTH) or corticotropin, is a hormone produced by the anterior pituitary gland in response to biological stress by effecting the increased production and release of corticosteroids(a)
Isolated adrenocorticotropic hormone deficiency presenting with hypercalcemia in a patient on long-term hemodialysis
There is a report of a report on a 44-year-old female hemodialysis (HD) patient who presented with hypercalcemia secondary to isolated adrenocorticotropic hormone (ACTH) deficiency. She had been suffering from nausea and abdominal pain caused by recurrent esophageal ulcer. Blood calcium (Ca) adjusted for serum albumin concentration was increased to 14.9 mg/dL (3.72 mmol/L) concurrently with fever and hypotension. Serum intact parathyroid hormone (PTH)-related peptide was not elevated, but serum intact PTH and 1,25-(OH)2 vitamin D3 were decreased to 31 pg/mL (ng/L) and 8.1 pg/mL (2.6 pmol/L), respectively. This case suggested that secondary adrenal insufficiency caused by isolated ACTH deficiency could be an occult cause of severe hypercalcemia in HD subjects(18).
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Sources
(a) http://en.wikipedia.org/wiki/Adrenocorticotropic_hormone
(18) http://www.ncbi.nlm.nih.gov/pubmed/12900850 http://medicaladvisorjournals.blogspot.com
Source: http://medicaladvisorjournals.blogspot.com/2013/10/isolated-adrenocorticotropic-hormone.html
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