Read the Beforeitsnews.com story here. Advertise at Before It's News here.
Profile image
Story Views
Now:
Last hour:
Last 24 hours:
Total:

Herbal Green Tea and Its Bioactive Epigallocatechin gallate (EGCG) in Ameliorated Risk, Progression and Treatment of Amyotrophic Lateral Fclerosis (Lou Gehrig's disease)

% of readers think this story is Fact. Add your two cents.


Kyle J. Norton 
 

Green tea may have a therapeutic and positive effect in reduced risk, progression and treatment of amyotrophic lateral sclerosis (ALS), some scientists suggested.

Green tea is a precious drink processed numbers of health benefit and known to almost everyone in Asia and Western world.

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a specific disease involved the death of neurons in controlling voluntary muscles.

 

According to the research published by the Hanyang University, administration of green tea Epigallocatechin gallate (EGCG) exerted a neuroprotective effect in reduced oxidative stress in orchestrated death of neurons.

In the evaluation of green tea EGCG in risk of amyotrophic lateral sclerosis (ALS) in human G93A(with function in responsible for destroying free superoxide radicals in the body) mutated Cu/Zn-superoxide dismutase (SOD1) gene in mice model, scientists found that

application of green tea EGCG at doses of 1.5, 2.9, and 5.8 microg/g body weight, dissolved in 0.5 ml of 0.9% sterile NaCl intraorally every day after 60 days of age demonstrate significant effects in prolonged the symptom onset  and life span of ALS mice through preserved more survival and attenuated death signals.

 

The result of increased life span of mutated gene mice was attributed to increased antioxidant activity of green tea in inhibited the levels of ROS in reduced cytotoxicity in initiated death of neurons in controlling voluntary muscles.

Further analysis of the effect of green tea in mutated SOD1-G93A in transgenic mice and wild-type mice randomly divided into EGCG-treated groups (10 mg/kg, p.o) and vehicle-treated control groups to assess the motor function, starting at the age of 70 days researchers found that injection of green tea treatment mice display a strong effect in delayed the onset of disease, and extended life span, similar to those in the Hanyang study.

 

Additional differentiation also indicated that green tea treatment group stimulated the production of numbers of new motor neurons in compared to control mice,

Interestingly, the application also decreased the over expression of microglial activation in initiated the inflammatory response due to neuronal damage and removed the damaged cells caused by phagocytosis production.

Prolonged and over expression of inflammatory cytokines may increase risk of neuron damage and in some cases death of the nerve cells.

Researchers in depth analysis showed that green tea reduced immunohistochemical reaction of NF-kappaB in response to the neuron damage (by antigens) through stimulated production of pro inflammatory factors (as antibody) and cleaved caspase-3 in induction of neuron apoptosis.

 

Moreover, application of green EGCG also expressed a similar result as in other studies in decreased protein level of iNOS and NF-kappaB in the spinal cords in orchestrated free radical NO levels and  inflammatory cytokines in neuron cell death in the spinal cord involving the onset of ALS.

 

Dr. Xu Z, the lead author after taking into account of other co founders said, “this study provides further evidences that EGCG has multifunctional therapeutic effects in the mouse model of ALS”.

 

These result were supported by the study of the green tea effect in risk of Lou Gehrig’s disease through reviewing the food selection of 44-item food frequency questionnaire of 1 million men and women enrolled and conducted in 1989 through 2002 for ALS mortality.

According to results of the study, researchers at the Harvard School of Public Health suggested that green tea injection is associated to reduced mortality rate of patients.

 

The information findings suggested that green tea and its bioactive polyphenol Epigallocatechin gallate (EGCG) may be considered as a function food for reduced risk and used combination with standard medicine in delayed progression and treatment of Amyotrophic lateral sclerosis (ALS).
For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA For Women 
 

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half  

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

 

Sources
(1) Diet and amyotrophic lateral sclerosis by Morozova N1, Weisskopf MG, McCullough ML, Munger KL, Calle EE, Thun MJ, Ascherio A.(PubMed)
(2) Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis by Xu Z1, Chen S, Li X, Luo G, Li L, Le W.(PubMed)
(3) The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice by Koh SH1, Lee SM, Kim HY, Lee KY, Lee YJ, Kim HT, Kim J, Kim MH, Hwang MS, Song C, Yang KW, Lee KW, Kim SH, Kim OH.(PubMed)



Before It’s News® is a community of individuals who report on what’s going on around them, from all around the world.

Anyone can join.
Anyone can contribute.
Anyone can become informed about their world.

"United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.

Please Help Support BeforeitsNews by trying our Natural Health Products below!


Order by Phone at 888-809-8385 or online at https://mitocopper.com M - F 9am to 5pm EST

Order by Phone at 866-388-7003 or online at https://www.herbanomic.com M - F 9am to 5pm EST

Order by Phone at 866-388-7003 or online at https://www.herbanomics.com M - F 9am to 5pm EST


Humic & Fulvic Trace Minerals Complex - Nature's most important supplement! Vivid Dreams again!

HNEX HydroNano EXtracellular Water - Improve immune system health and reduce inflammation.

Ultimate Clinical Potency Curcumin - Natural pain relief, reduce inflammation and so much more.

MitoCopper - Bioavailable Copper destroys pathogens and gives you more energy. (See Blood Video)

Oxy Powder - Natural Colon Cleanser!  Cleans out toxic buildup with oxygen!

Nascent Iodine - Promotes detoxification, mental focus and thyroid health.

Smart Meter Cover -  Reduces Smart Meter radiation by 96%! (See Video).

Report abuse

    Comments

    Your Comments
    Question   Razz  Sad   Evil  Exclaim  Smile  Redface  Biggrin  Surprised  Eek   Confused   Cool  LOL   Mad   Twisted  Rolleyes   Wink  Idea  Arrow  Neutral  Cry   Mr. Green

    MOST RECENT
    Load more ...

    SignUp

    Login

    Newsletter

    Email this story
    Email this story

    If you really want to ban this commenter, please write down the reason:

    If you really want to disable all recommended stories, click on OK button. After that, you will be redirect to your options page.