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An Experimental Peptide May Block Coronaviruses’ Ability To Enter Human Cells

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MIT chemists have designed a peptide that can bind to part of the coronavirus spike protein, which they hope may prevent the virus from being able to enter cells. Credit: Christine Daniloff, MIT

In hopes of developing a possible treatment for COVID-19, a team of MIT chemists has designed a drug candidate that they believe may block coronaviruses’ ability to enter human cells. The potential drug is a short protein fragment, or peptide, that mimics a protein found on the surface of human cells.

The researchers have shown that their new peptide can bind to the viral protein that coronaviruses use to enter human cells, potentially disarming it.

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