Infectious Diseases: The Anti Fungal Infection Whole Food

Kyle J. Norton, Master of Nutrition

 The finding of whole food medication by renowned scientists all over world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefits and patent right to producers.

Fungal infection is a common diseases  caused by over growth of fungus.
In other words, the immune system that protect the body against micro organisms has been overwhelming by the over growth of fungus.

People with weakened immune system such as cancer treatment, frequent use of antibiotics are associated to increase risk of fungal infection.

Patients with diabetes are also more prone to fungal infections. Fungal infection associated to diabetes include jock itch, athlete’s foot,….. and ringworm.

Depending to the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,…… and burning sensation.

In women, signs of yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,…….. and unusual vaginal discharge.

In men, signs of yeast infection may include burnding and itching around the head of the penis,
redness and swelling, pain during urination or sex,….. an small, rash-like bumps.  

If you experience some of the signs and symptoms indicated above, you may be infected by yeast. Please check with your doctor as soon as possible.

If you are given topical creams, oral medicine or anti fungal injection, please make sure you understand the common and serious of side effects before applying.

Garbanzo bean(Chickpea) and its bioactive phytochemicals may be considered as anti fungal function food in prevention and treatment of over growth of fungal species, some scientists suggested.

Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae.

It is one of the earliest cultivated vegetables in mankind, native to Middle East.

The joint study lead by the ICAR-Indian Agricultural Research Institute suggested, chickpea with abundant bioactive compounds may be used along with the relevant antioxidant capacities as anti fungal whole food, through expression of defense related enzymes like l-phenylalanine ammonia lyase, peroxidase and polyphenol oxidase(1).
Phenylalanine ammonia lyase is an enzyme that converts ammonia and trans-cinnamic acid involved properly function of neuro function(7) .

Peroxidase and polyphenol oxidase are antioxidants  that inhibit over expression of free radicals.

According to the study by the All India Institute of Medical Sciences, in the emergence of epidemic fungal pathogenic resistance to current antifungal drugs, C-25 found in Garbanzo beans(Chickpea) not only processes an effective antimycoticity but also antiproliferative agent against human oral cancer cells(2).

In support to the above, chickpea is found to exhibit inhibitory activity against Aspergillus flavus in a study conducted by the South China Normal University(3).

Cicerfuran, 2-(2-methoxy-4,5-methylenedioxyphenyl)-6-hydroxybenzofuran, phytoalexin and cicerfuran showed antimicrobial activity with MICs as low as 25microg/ml against Bacillus subtilis and Pseudomonas syringae, and four species of filamentous fungi, Aspergillus niger, Botrytis cinerea, Cladosporium herbarum and Monilinia aucupariae(4).

Other antioxidant such as Cicerarin(5), Cicerin(6) and arietin(6) may also be considered as 
novel chickpea peptides with differently anti fungal potencies.

Taken altogether garbanzo bean(chickpea) may be consideres as functional food for prevention and treatment of fungal infection. People with  high risk of fungal infection may want to add a portion garbanzo bean(chickpea) which processes abundant biobactive compounds  into daily diet for preventive measure.

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Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Development of Mesorhizobium ciceri-Based Biofilms and Analyses of Their Antifungal and Plant Growth Promoting Activity in Chickpea Challenged by Fusarium Wilt. by Das K1, Rajawat MVS1, Saxena AK1,2, Prasanna R1.(PubMed)
(2) Antifungal and antiproliferative protein from Cicer arietinum: a bioactive compound against emerging pathogens by Kumar S1, Kapoor V2, Gill K1, Singh K1, Xess I3, Das SN2, Dey S1(PubMed)
(3) Some 2S albumin from peanut seeds exhibits inhibitory activity against Aspergillus flavus by Duan XH1, Jiang R, Wen YJ, Bin JH.(PubMed)
(4) Antibacterial and antifungal activity of cicerfuran and related 2-arylbenzofurans and stilbenes by Aslam SN1, Stevenson PC, Kokubun T, Hall DR.(PubMed)
(5) Cicerarin, a novel antifungal peptide from the green chickpea byChu KT1, Liu KH, Ng TB.(PubMed)
(6) Cicerin and arietin, novel chickpea peptides with different antifungal potencies by Ye XY1, Ng TB, Rao PF.(PubMed)
(7) Effects of cinnamic acid on memory deficits and brain oxidative stress in streptozotocin-induced diabetic mice by Hemmati AA1, Alboghobeish S2, Ahangarpour A(PubMed).