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Scary as Hell! Soul-less Human-Animal Chimeras Now Grown On U.S. Research Farms! (Videos)

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12 Jan 16


We are NOT kidding here!

A radical new approach to generating human organs is to grow them inside pigs or sheep. WHAT are we DOING?! Have we NO MORAL GROUND anymore?


Human-Animal Chimeras Gestating on US Research Farms

Chimeras–animal embryos with human DNA–are gestating on research farms in the US. Also: DARPA working to develop super soldiers, the passing of pop icon David Bowie, and is Pakistan’s nuke threat against Iran related to Jeremiah’s prophecy against Elam?



Human-Animal Chimeras Are Gestating on U.S. Research Farms

A radical new approach to generating human organs is to grow them inside pigs or sheep.

By Antonio Regalado

Braving a funding ban put in place by America’s top health agency, some U.S. research centers are moving ahead with attempts to grow human tissue inside pigs and sheep with the goal of creating hearts, livers, or other organs needed for transplants.

The effort to incubate organs in farm animals is ethically charged because it involves adding human cells to animal embryos in ways that could blur the line between species.

Last September, in a reversal of earlier policy, the National Institutes of Healthannounced it would not support studies involving such “human-animal chimeras” until it had reviewed the scientific and social implications more closely.

The agency, in a statement, said it was worried about the chance that animals’ “cognitive state” could be altered if they ended up with human brain cells.

The NIH action was triggered after it learned that scientists had begun such experiments with support from other funding sources, including from California’s state stem-cell agency. The human-animal mixtures are being created by injecting human stem cells into days-old animal embryos, then gestating these in female livestock.

Based on interviews with three teams, two in California and one in Minnesota, MIT Technology Review estimates that about 20 pregnancies of pig-human or sheep-human chimeras have been established during the last 12 months in the U.S., though so far no scientific paper describing the work has been published, and none of the animals were brought to term.

The extent of the research was disclosed in part during presentations made at the NIH’s Maryland campus in November at the agency’s request. One researcher, Juan Carlos Izpisua Belmonte of the Salk Institute, showed unpublished data on more than a dozen pig embryo containing human cells. Another, from the University of Minnesota, provided photographs of a 62-day-old pig fetus in which the addition of human cells appeared to have reversed a congenital eye defect.

The experiments rely on a cutting-edge fusion of technologies, including recent breakthroughs in stem-cell biology and gene-editing techniques. By modifying genes, scientists can now easily change the DNA in pig or sheep embryos so that they are genetically incapable of forming a specific tissue. Then, by adding stem cells from a person, they hope the human cells will take over the job of forming the missing organ, which could then be harvested from the animal for use in a transplant operation.

“We can make an animal without a heart. We have engineered pigs that lack skeletal muscles and blood vessels,” says Daniel Garry, a cardiologist who leads a chimera project at the University of Minnesota. While such pigs aren’t viable, they can develop properly if a few cells are added from a normal pig embryo. Garry says he’s already melded two pigs in this way and recently won a $1.4 million grant from the U.S. Army, which funds some biomedical research, to try to grow human hearts in swine.

“The specter of an intelligent mouse stuck in a laboratory somewhere screaming ‘I want to get out’ would be very troubling to people.”

Because chimeras could provide a new supply of organs for needy patients and also lead to basic discoveries, researchers including Garry say they intend to press forward despite the NIH position. In November, he was one of 11 authors who published a letter criticizing the agency for creating “a threat to progress” that “casts a shadow of negativity” on their work.

The worry is that the animals might turn out to be a little too human for comfort, say ending up with human reproductive cells, patches of people hair, or just higher intelligence. “We are not near the island of Dr. Moreau, but science moves fast,” NIH ethicist David Resnik said during the agency’s November meeting. “The specter of an intelligent mouse stuck in a laboratory somewhere screaming ‘I want to get out’ would be very troubling to people.”

The chance of an animal gaining human consciousness is probably slim; their brains are just too different, and much smaller. Even so, as a precaution, researchers working with farm-animal chimeras haven’t yet permitted any to be born, but instead are collecting fetuses in order to gather preliminary information about how great the contribution of human cells is to the animals’ bodies.

Injecting cells from one species into the embryo of another creates mixtures called chimeras. From left to right: an ordinary mouse, a mouse that’s partly rat, a rat that’s partly mouse, a white rat.

Hiromitsu Nakauchi, a stem-cell biologist at Stanford University, began trying to make human-sheep chimeras this year. He says that so far the contribution by human cells to the animals’ bodies appears to be relatively small. “If the extent of human cells is 0.5 percent, it’s very unlikely to get thinking pigs or standing sheep,” he says. “But if it’s large, like 40 percent, then we’d have to do something about that.”

Other kinds of human-animal chimeras are already widely used in scientific research, including “humanized” mice endowed with a human immune system. Such animals are created by adding bits of liver and thymus from a human fetus (collected after an abortion) to a mouse after it is born.

The new line of research goes further because it involves placing human cells into an animal embryo at the very earliest stage, when it is a sphere of just a dozen cells in a laboratory dish. This process, called “embryo complementation,” is significant because the human cells can multiply, specialize, and potentially contribute to any part of the animal’s body as it develops.

In 2010, while working in Japan, Nakauchi used the embryo complementation method to show he could generate mice with a pancreas made entirely of rat cells. “If it works as it does in rodents,” he says, “we should be able have a pig with a human organ.”

“What if the embryo that develops is mostly human? It’s something that we don’t expect, but no one has done this experiment, so we can’t rule it out.”

Although Nakauchi was a star scientist, Japanese regulators were slow to approve his idea for chimeras—a “pig man” as critics put it—and by 2013 Nakauchi decided to move to the U.S., where no federal law restricts the creation of chimeras. Stanford was able to recruit him with the help of a $6 million grant from the California Institute of Regenerative Medicine, a state agency set up a decade ago to bypass political interference from Washington.

While the NIH funding ban doesn’t affect Nakauchi, it has put researchers under pressure to explain the purpose of their work. “I want to show you some chimeras,” Nakauchi said when I visited his laboratory at Stanford last month. He opened the door to a small room containing incubators where the chimeric embryos are stored. Because an early embryo is almost invisible to the human eye, the room houses special microscopes equipped with micro-needles used to inject the human cells into them.

The type of human cells being added are called iPS cells, made from skin or blood chemically reprogrammed into more versatile stem cells using a Nobel Prize-winning formula developed by one of Nakauchi’s Japanese colleagues. Nakauchi says that as a matter of convenience, most of the iPS cells his team has been placing into animal embryos are made from his own blood, since recruiting volunteers involves too much paperwork.

“We need a special consent if we’re injecting into animals,” he says sheepishly. “So I try to use my own.”

A pig at the swine unit of the University of California, Davis. Scientists hope to grow human organs in such animals.

The word chimera comes from the creature of Greek myth, part lion, part goat, and part snake. Nakauchi says most people at first imagine his chimeras are monsters, too. But he says attitudes change if he can explain his proposal. One reason is that if his iPS cells develop inside an animal, the resulting tissue will actually be his, a kind of perfectly matched replacement part. Desperately ill people on organ waiting lists might someday order a chimera and wait less than a year for their own custom organ to be ready. “I really don’t see much risk to society,” he says.

Before that can happen, scientists will have to prove that human cells can really multiply and contribute effectively to the bodies of farm animals. That could be challenging since, unlike rats and mice, which are fairly close genetically, humans and pigs last shared an ancestor nearly 90 million years ago.

To find out, researchers in 2014 decided to begin impregnating farm animals with human-animal embryos, says Pablo Ross, a veterinarian and developmental biologist at the University of California, Davis, where some of the animals are being housed. Ross says at Davis he has transferred about six sets of pig-human embryos into sows in collaboration with the Salk Institute and established another eight or 10 pregnancies of sheep-human embryos with Nakauchi. Another three dozen pig transfers have taken place outside the U.S., he says.

These early efforts aren’t yet to make organs, says Ross, but more “to determine the ideal conditions for generating human-animal chimeras.” The studies at Davis began only after a review by three different ethics committees, and even then, he says, the university decided to be cautious and limit the time the animals would be allowed to develop to just 28 days (a pig is born in 114 days).

By then, the embryonic pig is only half an inch long, though that’s developed enough to check if human cells are contributing to its rudimentary organs.

“We don’t want to grow them to stages we don’t need to, since that would be more controversial,” says Ross. “My view is that the contribution of human cells is going to be minimal, maybe 3 percent, maybe 5 percent. But what if they contributed to 100 percent of the brain? What if the embryo that develops is mostly human? It’s something that we don’t expect, but no one has done this experiment, so we can’t rule it out.” SOURCE




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    Your Comments
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    Total 30 comments
    • The Clucker

      I see they’ve finally figured out how to make a David Montaigne hybrid.

      • Central Scrutinizer

        HERE, HERE!!!!!

        A comment most worthy of 48 Super Secret Bonus Points.

        Enjoy, but don’t spend them all on Amazon books (despite poor David’s being relegated to the Discount Bargain Bin)………..




        See what I did there? Bargain Bin, Before it’s News, BIN ?????? MAN I CRACK MYSELF UP :mrgreen:

        • The Clucker

          48 is a lot, but I’ll spend them wisely. Thank you.

          Also, the impostor David M. that has been peddling his book is in trouble. The REAL David has shown up to take the house back. You’ll find him in the comments here:

          • Central Scrutinizer

            I kinda like the ‘new’ David.

            Still won’t buy any books, but then, I am hoarding my personal stash of Super Secret Bonus Points.

            BBBBWWWAAAA HHHAAAAA HHHAAAA HA !!!! :mrgreen:

            • The Clucker

              Hoard away, CS. Hoard away.

            • Equalizer

              Come on “Central Scrotumizer” AKA “Pedophile Bob” and “Cluck you” AKA “Chicken $hit”. You are like the “Laurel and hardy” of buffoons on B4IN.


            • The Clucker

              Well, EQ, at least you made it through typing a whole comment without bragging about your land and your concealed weapons license. I give you 2 OBB points for your clown make up and ceaseless attempts to spread the clap.

            • The Clucker

              By the way, EQ, I don’t know who “Laurel and hardy” are, which renders your old man insult entirely ineffective. Next time maybe try ‘Beavis and Butt-head’ or something like that.

          • Problem, Reaction, Solution

            How about Forrest Gump… “Stupid is as stupid does”. Now keep your beak on topic as not to appear “stupid”.

            • The Clucker

              I’ll try. Thanks for the advice.

          • Nyyk4

            I know who Laurel and Hardy are and I am only 30! Cluck you better not say 30 is old man status :razz: LOL

      • Central Scrutinizer

        The opening to BlowHards video segment reminded me of when we were in Health Class, and they would show a video of sperm cells going off in all directions…..

        Pretty much how I envision BlowHard when his most recent month of AmWay orders are tallied at InfoWarsStore. :mrgreen:

      • Ambicatus

        i wuz like “sweet, more stuff to chop” and like that top pic is sculpture, REAL mis-creations are waaaay uglier, Only the True Creator can make rad sarcastic stuff like ducks, which are super-cute, but super rapey, i , for one, would love to see some bominations, a written aricle is all rad an stuff, but show us some pics man. or a vid of a trolloc eating some foo, that would rock

        • The Clucker

          I can agree with that. I like that you want more stuff to chop.

      • MikeSavage

        Are you sure it’s not K.O.S.?

    • Hurkulese

      although they are growin human organs with these animals the 1st pic of the pig with a human face is FAKE!!!

      • Leroy Winston

        “…the 1st pic of the pig with a human face is FAKE!!!”

        No shiit Sherlock; thanks for pointing that out, Columbo.

        ….although, admittedly, on first take I assumed it was just a normal newborn western baby :lol:

        • BEEF SUPREME

          Ha! How you say that wit such pelfect Amellican accent?

    • A Commentator

      You make your whole article garbage when you open up with a fake picture to trick people into being interested in something mundane that will be saving lives soon.

      Yes, yes, were playing god, blah blah blah. If you don’t like it, move to a third world country and die from a mosquito bite. I’ll take advances in medicine any day. And I bet you will too if you ever find yourself dying in a hospital bed.

      But just think, when a doctor saves your life with a heart grown in a pig, you can still give god all the credit.

    • InquisitiveMind

      You sure its not the offspring of dave camoron and the pig he had conjugals with?

    • magusincognito

      These reported abominations are exactly what placed the Anunnaki in deep sh*t (i.e. with Cosmic Law)! Perhaps, their off-spring believe it’s cute…imitating them? However, they only magnify the initial offense(s). In fact, if I am an Anunnaki, I’m saying: Stop it, you idiots- you making us look worse!

      • Astral Silence

        Wow…so the Anunnaki got in deep crap with Cosmic Law for making animatronic animal-things that were in an art gallery?

    • YourNumbr1Fan

      Human/animal mixtures (chimeras) is pretty weird stuff, but that’s science and there are uses for this particular science, believe it or not.
      And how do you know anything about the soul — or lack of — in such a creature? Do you believe it’s just possible that an animal, say a dog, might have a soul? I do. In fact, I believe that many animals have MUCH more of a soul than evil, greedy, perverted people. Every time I look into my little female Dachshund’s bright brown eyes, I see an innocent and vibrant soul in there. And if a human was mixed with some part of my Dachshund, I suspect that the human might be better off for it.

      I have been studying the traits and dispositions of the “lower animals” (so called) and contrasting them with the traits and dispositions of man. I find the result humiliating to me. ~Mark Twain, Letters from the Earth, 1907

    • unidentified

      there are people willing to spend a fortune on organ implants to extend their lives without concern where they came from, the labs can make huge financial profits that way just like they do with medical care and prescription drugs approved (and occasionally denied) by our governmental leadership/advisors

    • srsly1

      Well, I for one didn’t read past your opening picture. If you’re going to post fake images, how do I know anything else you say is real or made up.

      Check it…

    • Anonymous

      Brother Hodges is NOT going to like his picture as depicted at the top here.

      God Bless All Future Law Suits!!!

    • Busta Myth

      America hired thousands of NAZIS after WW2 in Project Paperclip, that’s why America now looks like a cross between NAZI Germany and the Looney Tunes…with Popcorn

      What did you think a bunch of sicko Nazis war criminals would build, other than military weapons and a Piggy looking Übermensch ? :neutral:

    • MikeSavage

      Due Diligence;
      Everyone and every living thing is soulless. No one has or posesses a soul, we ARE a soul when we are alive. Soul means living being. When the living being stops breathing in death, the soul dies. Soul and life are essentially synonyms. the scriptures clearly teach this. The soul that sinneth, it itself shall die. If a soul were immortal, how could it then die? the answer is that souls are living beings, not some separate part of us that survives our death. Scriptures say things like “nothing survives death”, and “dead souls”.

    • underdog

      so that is how thay make politicians . oink oink !!!!!

      • MikeSavage

        NO. Politicians are the result of anal sex pregnancies.




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