Disruptions In Our Internal Body Clock Increase Cancer Risk

May 21st, 2019

By April McCarthy

Guest writer for Wake Up World

While it’s reported that chronic disruptions of circadian rhythms, or internal body clocks, can lead to an increased risk of cancer, the underlying mechanisms by which the disturbances promote tumor growth had been largely unknown until now.

This internal clock, or circadian rhythm, controls when we sleep and wake and plays a role in other biological processes as well, such as temperature regulation and hormone production. Some people have internal body clocks that run longer than 24 hours, or at the very least have slower adapting mechanisms to the traditional daily cycle.

Agrarian cultures built their societies around sunlight, waking up with the sun to toil in the field and heading home as the sun lowered beneath the horizon. But the Industrial Revolution, and electricity in particular, brought the freedom to unshackle us from nature’s clock.

In a study published in the journal PLOS Biology, researchers at Penn Medicine show circadian disruptions trigger an increase in cell proliferation that, ultimately, shifts the cell-cycle balance and stimulates the growth of tumors in mice.

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