Carcinogenic effects of titanium dioxide nanoparticles in human gastric epithelial cells in vitro.
Abstract Title:
Effects of titanium dioxide nanoparticles in human gastric epithelial cells in vitro.
Abstract Source:
Biomed Pharmacother. 2013 Aug 23. Epub 2013 Aug 23. PMID: 24051123
Abstract Author(s):
Monica Catarina Botelho, Carla Costa, Susana Silva, Solange Costa, Alok Dhawan, Paula A Oliveira, João P Teixeira
Article Affiliation:
INSA National Institute of Health, Department of Health Promotion, Porto, Portugal; CECA Centre for the Study of Animal Science, ICETA, Porto University, Porto, Portugal. Electronic address: [email protected].
Abstract:
Manufacturing or using nanomaterials may result in exposure of workers to nanoparticles. Potential routes of exposure include skin, lung and gastrointestinal tract. The lack of health-based standards for nanomaterials combined with their increasing use in many different workplaces and products emphasize the need for a reliable temporary risk assessment tool. Therefore, the aim of this work was to explore the effects of different doses of titanium dioxide nanoparticles on human gastric epithelial cells in vitro. We analyzed proliferation by MTT assay, apoptosis by Tunel, migration by injury assay, oxidative stress by determining GSH/GSSG ratio and DNA damage by Comet assay on nanoparticle-treated AGS human gastric epithelial cell line in comparison to controls. We show and discuss the tumor-like phenotypes of nanoparticles-exposed AGS cells in vitro, as increased proliferation and decreased apoptosis. Our results demonstrate for the first time that nanoparticles induce tumor-like phenotypes in human gastric epithelial cells.
Article Published Date : Aug 22, 2013
Study Type : In Vitro Study
Copyright: Green Med Info
Source: http://rinf.com/alt-news/breaking-news/carcinogenic-effects-of-titanium-dioxide-nanoparticles-in-human-gastric-epithelial-cells-in-vitro/72808/?utm_source=rss&utm_medium=rss&utm_campaign=carcinogenic-effects-of-titanium-dioxide-nanoparticles-in-h
Anyone can join.
Anyone can contribute.
Anyone can become informed about their world.
"United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.
Please Help Support BeforeitsNews by trying our Natural Health Products below!
Order by Phone at 888-809-8385 or online at https://mitocopper.com M - F 9am to 5pm EST
Order by Phone at 866-388-7003 or online at https://www.herbanomic.com M - F 9am to 5pm EST
Order by Phone at 866-388-7003 or online at https://www.herbanomics.com M - F 9am to 5pm EST
Humic & Fulvic Trace Minerals Complex - Nature's most important supplement! Vivid Dreams again!
HNEX HydroNano EXtracellular Water - Improve immune system health and reduce inflammation.
Ultimate Clinical Potency Curcumin - Natural pain relief, reduce inflammation and so much more.
MitoCopper - Bioavailable Copper destroys pathogens and gives you more energy. (See Blood Video)
Oxy Powder - Natural Colon Cleanser! Cleans out toxic buildup with oxygen!
Nascent Iodine - Promotes detoxification, mental focus and thyroid health.
Smart Meter Cover - Reduces Smart Meter radiation by 96%! (See Video).