Study: Caffeine Makes Cannabis More Enjoyable
While researching into how cannabis interacts with other drugs in the brain, scientists inadvertently discovered why coffee and getting high go so well together. Caffeine reinforces the effects with THC, potentially making it more pleasurable.
To get a better grasp of how a substance affects the human brain, scientists sometimes look at the interaction between two drugs. To study THC, researchers gave squirrel monkeys (which have a long history of getting stoned in laboratories) the ability to get high with the pull of a lever, which triggered an intravenous release of THC from a small surgically implanted device.
After making the monkeys plenty familiar with the consequences of pulling the lever, they gave them doses of MSX-3, a water-soluble analog of caffeine. With 1 mg/kg (equivalent to less than half a cup of coffee for the average person), the squirrel monkeys pulled the lever less often than normal; and when they gave them 3 mg/kg (equivalent one or more cups of drip coffee), the monkeys pulled the lever even less. The caffeine-analog made it so they monkeys needed less THC to achieve the same effect.
After keeping the monkeys drug free as a rest period for the second part of the experiment, scientists gave them a shot of either THC or THC + MSX-3 (the caffeine analog), and then allowed them to pull the lever whenever they wanted to. After getting reintroduced to THC, all the monkeys started pulling the lever, but the ones who got an extra dose of MSX-3 pulled it more often.
Scientists conclude that A2A antagonist drugs, like caffeine, “potentiated the effect of threshold doses” of THC and its natural counterpart anandamide, causing a “reinforcing effect.” In layman’s terms, this basically means caffeine allows you to smoke less while still achieving the same effect, but caffeine also makes it harder to quit one or the other if you consume both. On the other hand, very small doses of caffeine, less than half a cup of drip coffee, could theoretically help you stop smoking pot because of how it effects the dose-response curve.
Be AWARE truthisscary.com
Source: http://truthisscary.com/2015/05/study-caffeine-makes-cannabis-more-enjoyable/
Anyone can join.
Anyone can contribute.
Anyone can become informed about their world.
"United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.
Before It’s News® is a community of individuals who report on what’s going on around them, from all around the world. Anyone can join. Anyone can contribute. Anyone can become informed about their world. "United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.
LION'S MANE PRODUCT
Try Our Lion’s Mane WHOLE MIND Nootropic Blend 60 Capsules
Mushrooms are having a moment. One fabulous fungus in particular, lion’s mane, may help improve memory, depression and anxiety symptoms. They are also an excellent source of nutrients that show promise as a therapy for dementia, and other neurodegenerative diseases. If you’re living with anxiety or depression, you may be curious about all the therapy options out there — including the natural ones.Our Lion’s Mane WHOLE MIND Nootropic Blend has been formulated to utilize the potency of Lion’s mane but also include the benefits of four other Highly Beneficial Mushrooms. Synergistically, they work together to Build your health through improving cognitive function and immunity regardless of your age. Our Nootropic not only improves your Cognitive Function and Activates your Immune System, but it benefits growth of Essential Gut Flora, further enhancing your Vitality.
Our Formula includes: Lion’s Mane Mushrooms which Increase Brain Power through nerve growth, lessen anxiety, reduce depression, and improve concentration. Its an excellent adaptogen, promotes sleep and improves immunity. Shiitake Mushrooms which Fight cancer cells and infectious disease, boost the immune system, promotes brain function, and serves as a source of B vitamins. Maitake Mushrooms which regulate blood sugar levels of diabetics, reduce hypertension and boosts the immune system. Reishi Mushrooms which Fight inflammation, liver disease, fatigue, tumor growth and cancer. They Improve skin disorders and soothes digestive problems, stomach ulcers and leaky gut syndrome. Chaga Mushrooms which have anti-aging effects, boost immune function, improve stamina and athletic performance, even act as a natural aphrodisiac, fighting diabetes and improving liver function. Try Our Lion’s Mane WHOLE MIND Nootropic Blend 60 Capsules Today. Be 100% Satisfied or Receive a Full Money Back Guarantee. Order Yours Today by Following This Link.
| Visits: | 1,707,656,825 |
| Stories: | 8,448,219 |
Whistler Blowers, Insiders
