Anti Aging: The Natural Remedy Used Popularly In Skin Care Products Against All Aspects of Aging, Medline Studies Reveal

Kyle J. Norton

 Skin aging is a natural process with skin expression of thinner, paler and pigmented spots, including age spots, liver spots.

Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)…, particularly, in aging cosmetic products.

Numbers of herbal whole foods and theirs phytochemicals have been found in many anti aging products and they are sold to general public with or without clinical and non clinical trials.

How many of these types of products are actually working, the numbers are vague, depending to who do you talk to.

According to the statistic, 10 of most common herbal plants may be consumed or only be used as topical application, include aloe vera, the first in the list, avocado, almond, henna, sandalwood, saffron, elder tree, neem, lavender and amla. The list may be altered, depending to specialist preferences.

Some researchers suggested that honey best known for its properties of dressing for wounds and burns, may be also used as cosmetic anti aging substance as it exerts emollient, humectant, soothing, and hair conditioning effects, keeps the skin juvenile and retards wrinkle formation, regulates pH and prevents pathogen infections, through its antioxidant activities(1).

Cosmetic products are very profitable business. Global anti-aging market is growing rapidly, the total sale may reach over $331.41 billion by 2021, according to Orbis Research

The causes of skin aging can be both intrinsic and extrinsic factors, Dr. Poljšak B and colleagues in the study of skin aging said, ” It is well accepted that oxidative stress contributes significantly to extrinsic skin aging, although findings point towards reactive oxygen species (ROS) as one of the major causes of and single most important contributor; not only does ROS production increase with age, but human skin cells’ ability to repair DNA damage steadily decreases over the years”(3).

Oxidative stress over expression in the outer skin layer due to environment stress and lifestyle and diet preferences may interfere the normal growth of healthy skin, leading to onset of skin aging. 

These results are actually caused by incapability of the body enzymes with function in stimulated production of antioxidants to counter the levels of free radicals and their domino effects, causing alternation of the ratio of antioxidants and reactive oxygen species in the host body in induction of skin aging..

Truly, intrinsic and extrinsic aging causes significant alter the skin structure and components, that subsequently can impair molecular characteristics and biochemical processes, suggested by Dr. Fang JY, the lead author at joint study lead by the Chang Gung University(2).

The list of preventable risk factors and common causes of skin aging can be interestingly, including
* UV exposure

* Makeup wipes
* Dirty makeup brushes
*Poor diet

* Stress, 

* Smoking

* Excessive alcohol intake

* Repetitive facial expressions

* Physical inactivity,……

Aloe Vera or Aloe Vera supplement may be used to delay skin aging degeneration, particularly, in  expression of wrinkle.

Aloe Vera is species of succulent plant in the genus Aloe, belongings to the Family Xanthorrhoeaceae, native to Sudan.

It is very popular and cultivated commercially, due to its health benefits.

The herbal medicine has been used for treatment of many kinds of ailments, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. 

Wrinkle is a skin degenerative condition caused by the loss of dermis and subcutaneous fat layer underneath the skin, leading to a slight line or fold on the skin, particular in the face.

According to the Food Ingredients & Technology Institute, daily oral intake of plant sterols of Aloe vera gel (Aloe sterol) significantly increases the skin barrier function, moisture, and elasticity in photoprotected skin, thus reducing risk of  skin wrinkle.

In a 12-week, randomized, double-blind, placebo-controlled study of 48 apparently healthy men (age range: 30-59 years; average: 45 years), given oral Aloe sterol supplementation for 12 weeks, at the end of week 12  researchers found that the application shows a significant improvement of the skin elasticity index in comparison to the baseline value.

Dr. Tanaka M, the lead author said, “Aloe sterol ingestion increased skin elasticity in the photodamaged skin of men aged <46 years, and “No Aloe sterol intake-dependent harmful phenomenon was observed during the intake period”.

Furthermore, in vitro, Aloe sterols increased production of collagen and hyaluronic acid, natural substance in skin response to connective, epithelial, and neural tissues. approximately two-fold and 1.5-fold, and promoted gene expression levels in human dermal fibroblasts.

In fact, daily application of Aloe sterol-containing Aloe vera gel powder (AVGP) significantly reduced facial wrinkles in women aged ≥40 years as well as stimulating collagen and hyaluronic acid production by human dermal fibroblasts.

Injection of Aloe Vera gel enhanced healthy skin through promoting elasticity (R2), net elasticity (R5), and biological elasticity (R7) scores and skin fatigue area F3, according to the Food Ingredients and Technology Institute 12 weeks study suggested.

Taking altogether, there is no doubt that oral and topical administration of aloe vera or aloe vera supplements may improve skin condition caused by skin degeneration in all aspects, but quality of amount intake should only be prescribed by related field specialist. 

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Kyle J. Norton, Scholar and Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Honey in dermatology and skin care: a review by Burlando B1, Cornara L(PubMed)
(2) Skin aging caused by intrinsic or extrinsic processes characterized with functional proteomics by Fang JY1,2, Wang PW3, Huang CH4, Chen MH5,6, Wu YR7, Pan TL(PubMed)
(3) Intrinsic skin aging: the role of oxidative stress by Poljšak B1, Dahmane RG, Godić A(PubMed)
(4) Effects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women by Tanaka M1, Misawa E1, Yamauchi K1, Abe F1, Ishizaki C2.(PubMed)
(5) Effects of Aloe Sterol Supplementation on Skin Elasticity, Hydration, and Collagen Score: A 12-Week Double-Blind, Randomized, Controlled Trial by Tanaka M1, Yamamoto Y, Misawa E, Nabeshima K, Saito M, Yamauchi K, Abe F, Furukawa F.(PubMed)
(6) Aloe sterol supplementation improves skin elasticity in Japanese men with sunlight-exposed skin: a 12-week double-blind, randomized controlled trial by Tanaka M1, Yamamoto Y2, Misawa E1, Nabeshima K1, Saito M1, Yamauchi K1, Abe F1, Furukawa F2.(PubMed)