Vitamin B12 and neurodegenerative disease and cognitive impairment
Home of Kyle J. Norton for The Better of Living & Living Health The vitamin B-complex are essential water-soluble vitamins, including vitamin B1(thiamine), vitamin B2 (riboflavin ), vitamin B3 (niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), biotin, folic acid and vitamin B12 (cobalamins).
Vitamin B12 (Cobalamins) not only plays an important vital role in fatty acid synthesis and energy production, but also is essential in the normal functioning of the brain and nervous system, and for the formation of blood.
Vitamin B12 and neurodegenerative disease and cognitive impairment
In the study to examine the relationship of Vitamin B12 and its effect on neurodegenerative disease and cognitive impairment, showed that Vitamin B12 levels in the subclinical low-normal range (<250 ρmol>vitamin B12 levels and may independently increase the risk for cognitive impairment. Vitamin B12 deficiency (<150 ρmol>cognitive impairment. Vitamin B12 supplements administered orally or parenterally at high dose (1 mg daily) were effective in correcting biochemical deficiency, but improved cognition only in patients with pre-existing vitamin B12 deficiency (serum vitamin B12 levels <150 ρmol>19.9 μmol/L).Conclusion: Low serum vitamin B12 levels are associated with neurodegenerative disease and cognitive impairment(1).
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22221769
http://medicaladvisorjournals.blogspot.com
2012-10-17 16:00:15
Source: http://medicaladvisorjournals.blogspot.com/2012/10/vitamin-b12-and-neurodegenerative.html
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