Dietary Chromium (chromium 3+)- Chromium picolinate and chromium histidinate protects against renal dysfunction

Home of Kyle J. Norton for The Better of Living & Living Health Chromium(chromium 3+) is a essential mineral for the body in fat and carbohydrate metabolism, found abundantly in Beef, Eggs, Chicken, Oysters, Wheat germ, Green peppers, Banana, Apple, Etc.
Chromium picolinate and chromium histidinate protects against renal dysfunctionIn the study to investigate the effects of chromium picolinate (CrPic) and chromium histidinate (CrHis) on nuclear factor-kappa B (NF-κB) and nuclear factor-E2-related factor-2 (Nrf2) pathway in the rat kidney by the Faculty of Veterinary Science, Firat University, the result show that in kidney tissue CrHis/CrPic increases Nrf2 level, parallelly decreases NF-κB and partially restores IκBα levels in HFD/STZ group, suggesting that CrPic and CrHis may play a role in antioxidant defense system via the Nrf2 pathway by reducing inflammation through NF-κβ p65 inhibition. Moreover, a greater reduction in NF-κB expression and greater increases in expressions of IκBα and Nrf2 in diabetic rats supplemented with CrHis than rats supplemented with CrPic suggest that CrHis has more favorable effects than CrPic(5).

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(5) http://www.ncbi.nlm.nih.gov/pubmed/22483164 http://medicaladvisorjournals.blogspot.com