Thyroid Disease : Hashimoto's thyroiditis (chronic lymphocytic thyroiditis) - The Complications

Home of Kyle J. Norton for The Better of Living & Living Health Thyroid is one of the largest endocrine glands found in the neck, below the Adam’s Apple with the function of regulating the body use of energy, make of proteins by producing its hormones as a result of the stimulation of thyroid-stimulating hormone (TSH) produced by the anterior pituitary.
Thyroid disease is defined as a condition of malfunction of thyroid. Hyperthyroidism is a condition in which the thyroid gland is over active and produces too much thyroid hormones. Hypothyroidism is a condition in which the thyroid gland is under active and produces very little thyroid hormones. Thyroid cancer is defined as condition in which the cells in the thyroid gland have become cancerous.
Hashimoto’s thyroiditis (chronic lymphocytic thyroiditis)
Hashimoto’s thyroiditis is an autoimmune disease in which the immune system attacks the thyroid gland of that mostly often leads an underactive thyroid gland (hypothyroidism). According to the study by the University of Pisa, Women with Hashimoto’s thyroiditis (HT)  suffer from a high symptom load independently from hypothyroidism, which results just a contributing factor to the development of the clinical syndrome. In agreement with these results, we recently reported on the presence of symptoms and signs consistent with fibromyalgia (FM) in patients with HT regardless thyroid dysfunction, focusing to the weight of anti-thyroid autoimmunity in the HT-associated clinical syndrome(a).
C.1. Complication
1. Goiter
The most frequent cause of goiter in children is a deficit of iodine, leading to endemia of goiter in the regions with insufficient supplementation of this element. Goiter occurs also in the course of autoimmunological diseases of the thyroid gland (Hashimoto disease, Graves’ disease),  According to the theory of goiter pathogenesis, excessive enlargement of the thyroid gland is due to adaptation of follicle cells of the gland aiming at neutralizing the impaired synthesis of the thyroid hormones caused by various intrathyroid, environmental and genetic factors/agents, according to the study by(9).

2. Coronary heart disease
Risk of subsequent coronary heart disease in patients with Hashimoto’s thyroiditis, according to the study by the Lund University/Region Skåne(10).

3. Selective memory deficit 
There is a report of a longstanding selective memory deficit in a euthyroid 45-year-old woman who was being treated with levothyroxine for Hashimoto thyroiditis. The patient had complained of memory problems and deterioration of her concentration skills for about 2 years, according to the study by the 1st University Department of Neurology(11).

4. Myxedema coma
There is a report of a case of myxedema coma caused by isolated thyrotropin stimulating hormone deficiency and Hashimoto‘s thyroiditis(12).

5. Impaired fertility and miscarriage
Autoimmune thyroid disease is the most common cause of thyroid dysfunction in pregnancy. Hashimoto’s thyroiditis is associated with impaired fertility and miscarriage, and may first manifest in pregnancy due to the increased thyroid hormone requirement., according to Bereich Forschung und Lehre des Zentrallabors, Universitätsklinikum Essen(13). 

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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/22147633
(9) http://www.ncbi.nlm.nih.gov/pubmed/16704860
(10) http://www.ncbi.nlm.nih.gov/pubmed/22438933
(11) http://www.ncbi.nlm.nih.gov/pubmed/22960439
(12) http://www.ncbi.nlm.nih.gov/pubmed/21206138
(13) http://www.ncbi.nlm.nih.gov/pubmed/21814886 http://medicaladvisorjournals.blogspot.com