How to Prevent Onset of Nonalcoholic Fatty Liver Disease Naturally, PubMed Studies Show
Kyle J. Norton
Anise may have a potential and substantial effect in reduced risk and treatment of nonalcoholic fatty liver disease, some scientists suggested.
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belongings to the family Apiaceae native to to Egypt and the Mediterranean region, used in traditional herbal medicine as fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic, ….
Chemical comstituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
Nonalcoholic fatty liver disease is medical condition characterized by fat accumulated in the liver tissue other than excessive consumption of alcohol.
According to statistic, nonalcoholic fatty liver disease is one of most common cause of liver disease with a prevalence rate of 20%–30% in Western world.
In the comparison the effect of anise fruit essential oil and extract and risk of nonalcoholic fatty liver disease, researchers at the Islamic Azad University conducted a experiment of 60 rats randomly divided into ten groups, six in each group with NAFLD induced by using choline-deficient diet for 90 days and followed by 30 days of treatment with 25, 50, 100, and 200 mg/kg/day of hydroethanolic extract (AE) as well as 0.125, 0.25, and 0.5 mg/kg/day of essential oil (AO), at the end of the experiment researchers found that both applications exert significantly reverse activities in increased AE and AO plasma levels of total cholesterol, low-density lipoprotein, and triacylglycerol and decrease in high-density lipoprotein level caused by choline-deficient diet in dose-dependent manner.
Additional differentiation also found that AE and AO reduced the elevated levels of enzymes aspartate transaminase (AST) and alanine transaminase (ALT) which are considered as an indication of either liver injure or damage caused by the acute inflammation in the experiential subject model.
Levels of aspartate aminotransferase (AST) is usually used as a maker to detect liver damage.
Low levels of ALT in the blood are associated to liver damage.
Observation of injection of anise AE and AO also exerted a powerful antioxidant activity in significant lower over expression of ROS in exhibited free radical chain reaction in induction of oxidative stress to precipitate liver toxicity.
According to the St. Louis University Health Sciences Center, over expression of free radicals in the liver can damage cellular macromolecules in over production in induction of hepatocellular injury.
Also, according to the histological findings, both AE and AO displayed a substantial effect in reduced macrovesicular steatohepatitis which is the leading cause of liver cancer.
Further analysis of the experiment, researchers found that both anise AE and AO demonstrated a strong effect in ameliorated lipid peroxidation induced by oxidative stress indicated by elevation of plasma level of 8-isoprostane which is correlated to the prevalence of non-alcoholic fatty liver disease (NAFLD).
Elevated 8-Isoprostane values activated by lipid peroxidation induced by injection of choline-deficient diet were also considered as a biomaker in patient with non alcoholic liver disease and correlated to with body mass index and total cholesterol in NAFLD but did not significantly related to sex, age, biochemical data or iron metabolism markers in all liver diseases.
Therefore, people with high body mass index and high levels of total cholesterol levels are susceptible to increase risk of the diseases.
Taken together, herbal Anise with abundant of bioactive chemical constituents and essential oil may be effective for reduced risk and treatment of non alcoholic liver disease, but intake of herbal extract should only prescribed by related field specialist in prevention of toxicity.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Pimpinella anisum L. fruit: Chemical composition and effect on rat model of nonalcoholic fatty liver disease by Asadollahpoor A1, Abdollahi M2, Rahimi R3,(PubMed)
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the highest onset of liver failure now is people consuming “energy” drinks,10 a day average will kill ya!
Papaya Seeds from very ripe Papaya – that have turned Black in Color for Liver.
I give it to people who Drink Alcohol a lot, it helps repair the Liver.
Papaya seeds contain nutrients that help heal cirrhosis of the liver and improve kidney health, preventing renal failure.
You are 100% right
Just wait for big pHarma to classify these essential oils as a “drug” so they can regulate, eliminate, and/or profit from them
I believe that
2 years ago I decided to have an ultra sound to determine why I suffered such debilitating menstrual cramps, my gyn only found a very small ovarian cyst and sent me on my way with some advil. a year later I started having chronic urinary type infections and on the 3rd visit was told I had a huge fibroid or cyst. I immediately had another ultra sound and found the cyst had grown to 7.5 centimeters. My gyn than wanted to do immediate surgery and explained that if they can’t drain it that most likely I would need a hysterectomy. When I asked why and how cyst occur, his only answer was that it is complicated. So I went home got on the Internet reviewed hundreds of web sites and found no reasonable explanation for cyst formation until coming upon a testimony on how Dr. Colle cured a woman from the ovarian cyst. At this point I was in chronic pain from the cyst pressing against my bladder, and had developed chronic odor in my urine for 6 months that even the antibiotics could not cure. I contacted Dr. Colle and he told me that his herbal medicine can get rid of the cyst. I ordered for the herbs and he prepared it and sent it to me through UPS Courier service and I got it after 3 working days.. I started taking the medicine as prescribed by him… I took the herbal medicine for 21 days. After using the herbal medicine for just 3 days the odor and pain started to diminish. after 3 weeks of taking the medicine, I went back to my gyn and I had another Ultra Sound, the Cyst was no longer found. it’s been more than 6 months I took the herbs and I have no symptoms everyone tells me I look a 100% better, I sleep better and feel fantastic. and the best bonus of all I HAVE NO MORE MENSTRUAL CRAMPS.
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