Earthquake-like Bursts of Intrinsic Arousal Activations in the Brain Found to be Essential for Sleep and Sleep-Stage Transitions
Sleep is traditionally considered to be a homeostatic process that resists deviation from equilibrium. In that regard, brief episodes of waking are viewed as perturbations that lead to sleep fragmentation and related sleep disorders. While addressing aspects of sleep regulation related to consolidated sleep and wake and the sleep-wake cycle, the homeostatic paradigm does not account for the dozens of abrupt sleep-stage transitions and micro-states within sleep stages throughout the night. Ivanov and colleagues hypothesized that, while sleep is indeed homeostatic at time scales of hours and days, non-equilibrium dynamics and criticality underlie sleep micro-architecture at shorter time scales.Findings link healthy sleep to brain-wave bursts that mathematically mimic earthquakes
Credit; Ivanov et al.
Their empirical findings and modeling indicate that arousals from sleep are a manifestation of an intrinsic non-equilibrium sleep regulatory mechanism related to self-organization of neuronal assemblies. This mechanism acts at time scales of seconds and minutes and stays on track via continuous bursts in brain wave rhythms.
The study also suggests that maintaining a non-equilibrium critical state is essential for the sleep-regulation system’s flexibility to spontaneously activate multiple transitions between different sleep stages and between sleep and brief wakefulness throughout the sleep period. Such critical state is also necessary for the complex sleep micro-architecture that is increasingly recognized to be characteristic of healthy sleep. The observed critical behavior in sleep draws parallels to other non-equilibrium systems at criticality, such as earthquakes.
“Paradoxically, we find that the ‘resting’ state of healthy sleep is maintained through bursts in cortical rhythm activity that obey similar temporal organization, statistics, and mathematical laws as earthquakes,” Ivanov says. “Our findings serve as building blocks to better understand sleep, and could help improve detection and treatment of sleep disorders.”
Contacts and sources:
Plamen Ch. Ivanov
Citation: Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture.
Jilin W. J. L. Wang, Fabrizio Lombardi, Xiyun Zhang, Christelle Anaclet, Plamen Ch. Ivanov. PLOS Computational Biology, 2019; 15 (11): e1007268 DOI: 10.1371/journal.pcbi.1007268
The article is freely available: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1007268
Source:
Anyone can join.
Anyone can contribute.
Anyone can become informed about their world.
"United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.
Before It’s News® is a community of individuals who report on what’s going on around them, from all around the world. Anyone can join. Anyone can contribute. Anyone can become informed about their world. "United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.
LION'S MANE PRODUCT
Try Our Lion’s Mane WHOLE MIND Nootropic Blend 60 Capsules
Mushrooms are having a moment. One fabulous fungus in particular, lion’s mane, may help improve memory, depression and anxiety symptoms. They are also an excellent source of nutrients that show promise as a therapy for dementia, and other neurodegenerative diseases. If you’re living with anxiety or depression, you may be curious about all the therapy options out there — including the natural ones.Our Lion’s Mane WHOLE MIND Nootropic Blend has been formulated to utilize the potency of Lion’s mane but also include the benefits of four other Highly Beneficial Mushrooms. Synergistically, they work together to Build your health through improving cognitive function and immunity regardless of your age. Our Nootropic not only improves your Cognitive Function and Activates your Immune System, but it benefits growth of Essential Gut Flora, further enhancing your Vitality.
Our Formula includes: Lion’s Mane Mushrooms which Increase Brain Power through nerve growth, lessen anxiety, reduce depression, and improve concentration. Its an excellent adaptogen, promotes sleep and improves immunity. Shiitake Mushrooms which Fight cancer cells and infectious disease, boost the immune system, promotes brain function, and serves as a source of B vitamins. Maitake Mushrooms which regulate blood sugar levels of diabetics, reduce hypertension and boosts the immune system. Reishi Mushrooms which Fight inflammation, liver disease, fatigue, tumor growth and cancer. They Improve skin disorders and soothes digestive problems, stomach ulcers and leaky gut syndrome. Chaga Mushrooms which have anti-aging effects, boost immune function, improve stamina and athletic performance, even act as a natural aphrodisiac, fighting diabetes and improving liver function. Try Our Lion’s Mane WHOLE MIND Nootropic Blend 60 Capsules Today. Be 100% Satisfied or Receive a Full Money Back Guarantee. Order Yours Today by Following This Link.
| Visits: | 1,814,936,355 |
| Stories: | 8,660,203 |
Whistler Blowers, Insiders
