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Marijuana and Vascular Dementia

Sunday, April 16, 2017 22:25
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(Before It's News)

The American College of Cardiology

As marijuana legalization spreads, new research is improving our understanding of side effects. Heart cells have cannabis receptors relevant to vascular squeezing ability. Learn about marijuana’s link to vascular dementia. 


WASHINGTON – Using marijuana raises the vascular risks of stroke and heart failure, major risk factors leading to vascular dementia. Even after accounting for demographic factors, other health conditions and lifestyle risk factors such as smoking and alcohol use, the data is compelling, according to research being presented at the American College of Cardiology’s 66th Annual Scientific Session.

Vascular Health

Coming at a time when marijuana, medically known as cannabis, is on track to become legal for medical or recreational use in more than half of U.S. states, this study sheds new light on how the drug affects vascular health. While previous marijuana research has focused mostly on pulmonary and psychiatric complications, the new study is one of only a handful to investigate cardiovascular outcomes. 

“Like all other drugs, whether they’re prescribed or not prescribed, we want to know the effects and side effects of this drug,” said Aditi Kalla, MD, Cardiology Fellow at the Einstein Medical Center in Philadelphia and the study’s lead author. “It’s important for physicians to know these effects so we can better educate patients, such as those who are inquiring about the safety of cannabis or even asking for a prescription for cannabis.”

Nationwide Inpatient Sample

The study drew data from the Nationwide Inpatient Sample, which includes the health records of patients admitted at more than 1,000 hospitals comprising about 20 percent of U.S. medical centers. Researchers extracted records from young and middle-aged patients—age 18-55 years—who were discharged from hospitals in 2009 and 2010, when marijuana use was illegal in most states. 

Marijuana use was diagnosed in about 1.5 percent (316,000) of more than 20 million health records included in the analysis. Comparing cardiovascular disease rates in these patients to disease rates in patients not reporting marijuana use, researchers found marijuana use was associated with a significantly increased risk for cardiovascular events such as stroke, heart failure, coronary artery disease and sudden cardiac death.

Marijuana – Independent Association

Marijuana use was also linked with a variety of factors known to increase cardiovascular risk, such as obesity, high blood pressure, smoking and alcohol use. After researchers adjusted the analysis to account for these factors, marijuana use was independently associated with a 26 percent increase in the risk of stroke and a 10 percent increase in the risk of developing heart failure. 

“Even when we corrected for known risk factors, we still found a higher rate of both stroke and heart failure in these patients, so that leads us to believe that there is something else going on besides just obesity or diet-related cardiovascular side effects,” Kalla said. “More research will be needed to understand the pathophysiology behind this effect.”

 
Heart Cells Have Canabis Receptors
 
Research in cell cultures shows that heart muscle cells have cannabis receptors relevant to contractility, or squeezing ability, suggesting that those receptors might be one mechanism through which marijuana use could affect the cardiovascular system. It is possible that other compounds could be developed to counteract that mechanism and reduce cardiovascular risk, Kalla said. 

Because the study was based on hospital discharge records, the findings may not be reflective of the general population. The study was also limited by the researchers’ inability to account for quantity or frequency of marijuana use, purpose of use (recreational or medical), or delivery mechanism (smoking or ingestion).

Further Insights

Kalla suggested that the growing trend toward legalization of marijuana could mean that patients and doctors will become more comfortable speaking openly about marijuana use, which could allow for better data collection and further insights into the drug’s effects and side effects. 

SOURCE:

  • The American College of Cardiology
    The American College of Cardiology is a 52,000-member medical society that is the professional home for the entire cardiovascular care team. The mission of the College is to transform cardiovascular care and to improve heart health. The ACC leads in the formation of health policy, standards and guidelines. The College operates national registries to measure and improve care, offers cardiovascular accreditation to hospitals and institutions, provides professional medical education, disseminates cardiovascular research and bestows credentials upon cardiovascular specialists who meet stringent qualifications.

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Source: http://dementiaviews.blogspot.com/2017/04/marijuana-vascular-dementia.html

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Total 4 comments
  • desertspeaks

    FROM THE SAME PEOPLE THAT TELL YOU POISONS IN VACCINES, RADIATION, FRANKENFOOD ETC ETC ETC are good for you!
    Sorry, not buying their lies any more!

  • VirusGuard

    A bit of weed now and then is good for your mental health and can be good for your sex life.

    Life is for living, everything you like has bad side effects accorinding to doctors who still cannot cure the common cold and if you have a bad heart then don’t get too high would be my advise and try to make the misses do all the work during sex sessions.

    Working like debt slaves just to cover the rent is killing people but no one is granting planing permision to bring costs down using new builds and the laws of supply and demand are they now so lets not pretend that they give a shit about peoples health or lives.

  • Sucking Chest Wound

    Why have humans got receptors for an “illegal” medicine?

    Did god get it wrong?

    Why did the three wise kings gift Jesus with gold (golden oil) frankincense and myrrh?

    Gold: would Jesus have need for a precious metal? Or would that gift look awfully crass, considering.
    ( Canabis oil is often called golden oil and is mentioned in the bible.)

    Frankincense and Myrrh aid the “golden oil” in healing, and was used widely down through history. The earliest I could find records of its use as a medicine was 5,000 bc.

    So, was the thought behind offering the gifts to Jesus, richness?….. or good health, you think?
    Remember, none of the above naturally occurring items were deemed illegal until around 1929? …..That’s when drug companies lobbied governments to demonise this naturally occurring medicine to enable rich pharmaceutical companies to promote their own chemical poisons.
    Remember, it’s not about you.
    Pharmaceutical companies don’t love you, governments don’t love you, they’re not your friends……It’s all about the profit margin.

    You: I’m sick.
    Them: So sad. how much did you earn last year?
    You: $$$
    Them: good….send it to us.

    Dandelion tea. An old and trusted curative.

    Camomile tea: Two active ingredients mmmm…. and healthy too.

    Slippery elm bark: Five active ingredients. Better known as Aspro for headaches and fevers.

    Canabis oil: Eighty four active ingredients. No side effects. Off to jail with you.

    Once again, why do we have two naturally occurring receptors for this cure?….Evolution?…..and who wrote this report? A pharmaceutical troll?

  • Deputy Dawg

    Yea, yea, yea and all the subjects in the study drank H2o as well proving beyond any reasonable doubt, at least this week in their minds that water increases ones chance of developing heart disease. Theses abstract findings are based solely on assumptions and speculation! They have not provided a single piece of solid evidence that would legitimately suggest any true association between pot and heart disease. Big pharmaceutical companies conduct or sponsor these ridiculous studies trying desperately to discredit the many medical benefits of marijuana. They don’t want competition. They hate the fact that people in pain can grow and use marijuana by themselves without being treated by healthcare professionals like pill seekers and low life junkies participating in court ordered drug diversion programs simply for asking for relief of pain.

    I would like to see an actual study evaluating the combination of bitter lettuce and marijuana used as a pain reliever. Bitter lettuce which can be found growing wild nearly everywhere was once relied on as a non-addictive alternative to opium. I haven’t tried it personally but it’s said that marijuana buds can be soaked in the white milky sap of the plant then dried for smoking. The combination of the two compounds is believed by some to increase the effectiveness of both as a painkillers. If true think of all the possible benefits to suffering patients.

    Deputy Dawg

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