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Congratulations to Dr. Kattel

Wednesday, November 14, 2012 2:50

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Krishna Kattel (Dr. Kattel now) completed his PhD from Kyungpook National University, Korea.

Congratulations Dr. Kattel.

His thesis title was:

“Synthesis, Characterization, In Vitro and In Vivo Studies of Lanthanide Oxide/Hydroxide Nanostructures for Magnetic Resonance Imaging (MRI) Contrast Agent and Fluroscence Imaging (FI) Agent.”

The size, composition, and shape of the nanoparticles are tuned by controlling reaction conditions. These nanoparticles are made dispersible in various media through proper surface modifications. The effects of particle size, shape, composition, and interparticle spacing on physical and chemical properties of the nanostructures are addressed by my research. I accomplished the synthesis of a series of biocompatible multifunctional magnetic nanoparticles for highly efficient diagnostic and therapeutic applications. In addition, I synthesized various paramagnetic lanthanide oxide nanoparticles for advanced T1 and T2 MRI contrast agents. I demonstrated the applicability of antibody conjugated iron oxide nanoparticles for cancer cell separation in buffer and IO-Ab nanoparticles to capture cancer cells without pre-treatment process.

As an extension of my research, I am planning to do further research on gold nanoparticles for a wide range of biological studies. Through precise control over the particle morphology and surface modification, I plan to design and create gold nanostructures that can be used for applications such as bio-sensing and therapeutics.

More on Dr. Kattel’s can be found on his publications.
1) Kattel, K.; Park, J. Y.; Xu et al. “A Facile Synthesis, In Vitro and In Vivo MR Studies of D-glucuronic Acid Coated Ultrasmall Ln2O3 (Ln = Eu, Gd, Dy, Ho and Er) Nanoparticles as a New potential MRI Contrast Agent.” ACS Applied Materials and Interfaces, 2011, 3, 3325-3334. (IF:4.5)

2) Kattel, K. et al.; “Water–Soluble Ultrasmall Eu2O3 Nanoparticles as a Fluorescent Imaging (FI) Agent: In Vitro and In Vivo Studies.” Colloids and Interfaces A: Physiochemical and Engineering Aspects 2012, 394, 85-91. (IF: 2.3).

3) Kattel, K.; Park, J. Y.; Xu, W.; Kim, H. G.; Lee, E. J.;et al. “Paramagnetic Dysprosium Oxide Nanoparticles and Dysprosium Hydroxide Nanorods as new T2 MRI contrast agent.” Biomaterials 2012, 33, 3254-3261. (IF: 7.88).

4) Xu, W.*; Kattel, K.*; Park, J. Y.*; Chang, Y.; Kim, T. J.; Lee, G. H. “Paramagnetic Nanoparticle T1 and T2 MRI Contrast Agents.” Phys. Chem. Chem. Phys. 2012, 14, 12687-12700. [*authors have equal contributions]. (IF. 3.6)
5) Kattel. K. et al. “Surface Coated Eu(OH)3 Nanorods: A Facile Synthesis, Characterization, MR Relaxivities and In Vitro Cytotoxicity.” Journal of Nanoscience and Nanotechnology. (Just accepted).

2012-11-14 02:42:37

Source: http://www.nepachemistry.com/2012/11/congratulations-to-dr-kattel.html

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