Interactive Map Reveals Your Genetic History
The interactive map, produced by researchers from Oxford University and UCL, details the histories of genetic mixing between each of the 95 populations across Europe, Africa, Asia and South America spanning the last four millennia.
The study, published this week in Science, simultaneously identifies, dates and characterises genetic mixing between populations. To do this, the researchers developed sophisticated statistical methods to analyse the DNA of 1490 individuals in 95 populations around the world. The work was chiefly funded by the Wellcome Trust and Royal Society.
“DNA really has the power to tell stories and uncover details of humanity’s past.” said Dr Simon Myers of Oxford University’s Department of Statistics and Wellcome Trust Centre for Human Genetics, co-senior author of the study.
“Because our approach uses only genetic data, it provides information independent from other sources. Many of our genetic observations match historical events, and we also see evidence of previously unrecorded genetic mixing. For example, the DNA of the Tu people in modern China suggests that in around 1200CE, Europeans similar to modern Greeks mixed with an otherwise Chinese-like population. Plausibly, the source of this European-like DNA might be merchants travelling the nearby Silk Road.”
The powerful technique, christened ‘Globetrotter’, provides insight into past events such as the genetic legacy of the Mongol Empire. Historical records suggest that the Hazara people of Pakistan are partially descended from Mongol warriors, and this study found clear evidence of Mongol DNA entering the population during the period of the Mongol Empire. Six other populations, from as far west as Turkey, showed similar evidence of genetic mixing with Mongols around the same time.
“What amazes me most is simply how well our technique works,” said Dr Garrett Hellenthal of the UCL Genetics Institute, lead author of the study. “Although individual mutations carry only weak signals about where a person is from, by adding information across the whole genome we can reconstruct these mixing events. Sometimes individuals sampled from nearby regions can have surprisingly different sources of mixing.
“For example, we identify distinct events happening at different times among groups sampled within Pakistan, with some inheriting DNA from sub-Saharan Africa, perhaps related to the Arab Slave Trade, others from East Asia, and yet another from ancient Europe. Nearly all our populations show mixing events, so they are very common throughout recent history and often involve people migrating over large distances.”
The team used genome data for all 1490 individuals to identify ‘chunks’ of DNA that were shared between individuals from different populations. Populations sharing more ancestry share more chunks, and individual chunks give clues about the underlying ancestry along chromosomes.
“Each population has a particular genetic ‘palette’”, said Dr Daniel Falush of the Max Planck Institute for Evolutionary Anthropology in Leipzig, co-senior author of the study. “If you were to paint the genomes of people in modern-day Maya, for example, you would use a mixed palette with colours from Spanish-like, West African and Native American DNA. This mix dates back to around 1670CE, consistent with historical accounts describing Spanish and West African people entering the Americas around that time. Though we can’t directly sample DNA from the groups that mixed in the past, we can capture much of the DNA of these original groups as persisting, within a mixed palette of modern-day groups. This is a very exciting development.”
As well as providing fresh insights into historical events, the new research might have implications for how DNA impacts health and disease in different populations.
“Understanding well the genetic similarities and differences between human populations is key for public health,” said Dr Simon Myers. “Some populations are more at risk of certain diseases than others, and drug efficacy is also known to vary significantly. Rare genetic mutations are particularly likely to show strong differences between populations, and understanding their role in our health is an area of intense current research efforts. We hope in future to include even more detailed sequencing, to spot these rare mutations and better understand their global spread. Our method should be even more powerful when applied to these future data sets, providing rich opportunities for future work.”
The research was funded by the Oxford University John Fell Fund, the National Institutes of Health (USA), the Wellcome Trust, the Biotechnology and Biological Sciences Research Council and the joint Royal Society/Wellcome Trust Sir Henry Dale Fellowship.
Clare Ryan
University College London
Source: http://www.ineffableisland.com/2014/02/interactive-map-reveals-your-genetic.html
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i made scribble lines and came to conclusion that EVERYONE came from Africa because I say so.
I second.
African does not mean black (which is just a Talmudic concept anyway). The people alive in Africa today are no less removed from their ancestors than Eurasians are.
Hah! All your Leprechauns belong to the Orcadian-Basque Liberation Army (Scots) you Irish losers!
Tocharian Xibo and Chinese civilization for the win!
Get that tartan off you filthy papist apes!
Well. I’m from Texas, so …I have absolutely no idea who I am or where I came from…so I really don’t even know where to begin on the map! Great. All I really have to go by is…what ?..my mother’s lineage or my fathers??? My last name? My race?..UGH!!! At this point in time aren’t we really all just a bunch of mutts? This is one of those things where you just leave it to the LORD God your maker and say Only God knows. What difference does it make really? ….unless you’re ‘royalty’….they kinda prefer amphibian DNA to human…just sayin’….
Yea..don’t worry. .they don’t know either. .they only think the do..
I am interested in where the 10 tribes of Israel went to. no one knows for sure. I’m thinking the other 3 tribes, Benjamin, levi, and some of the jews didn’t return to Israel either. they are said to be scattered and Yah will collect their seed (offspring) in the last days of earth. HE knows all. I find it interesting about the division of who keeps the Creator’s Laws and who dismisses the Laws in our time. us law keepers are few and far between. I believe in the Savior, just to let you know. peace to all.