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Best Way to Kill Deadly Bacteria Revealed by Computer

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Bacteria, transformed into dormant spores, can survive millions of years in extreme environments, threatening human life in the form of food poisoning and the biological weapon anthrax. But understanding how bacteria adapt to hostile environments has largely remained a mystery—until now.

In a new study, USC Viterbi professors Priya Vashishta, Rajiv K. Kalia and Aiichiro Nakano used computer-based models to identify mechanisms or “strategies” used by bacterial spores to evade attack from extreme temperatures, chemicals and radiation.

Sing complex mathematical techniques, a team of USC Viterbi researchers has determined the optimal conditions for killing harmful bacteria such as anthrax and E.coli. 
Photo/iStock.
Using complex mathematical techniques to examine spores at the molecular level, the team also determined the optimal conditions for killing harmful bacteria.

Vashishta, Kalia and Nakano have joint appointments with the USC Viterbi’s Department of Computer Science, the Mork Family Department of Chemical Engineering and Materials Science, and the USC Dornsife’s Department of Physics and Astronomy.

The researchers ran hundreds of thousands of simulations to trace the trajectory of the water molecules (yellow lines) in a crystal of dipicolinic acid (cyan lines), a chemical compound inside the spore that contains the bacterial DNA machinery.
Credit: USC

“Imagine bacterial spores are like a seed with a hard coating that preserves the DNA machinery,” says Vashishta, the director of USC’s Collaboratory for Advanced Computing and Simulations.

This hard coating acts as an armor protecting the spore. In this “freeze-dried,” almost lifeless state, the spores wait for the right conditions to bloom into harmful bacteria.

Earlier studies have shown that wet heat sterilization can destroy disease-causing bacteria, but the mechanisms whereby spores are killed by this treatment had not been fully revealed.

As such, optimizing the technique and assuring the destruction of bacterial spores with any degree of certainty has been a challenge for public health authorities and defense agencies.

Breaking down bacterial defenses

Using x-ray crystallography data, the researchers first determined the key elements of a single bacterium—water, acid and a calcium ion. Then, they used a supercomputer to run hundreds of thousands of simulations, controlling the percentage of acid, water and calcium, and watched what happened.

The simulations revealed that depending on water concentration and temperature, the water inside the bacterial cell behaves like either solid, gel or liquid.

“Our models showed the spores perform a kind of chemical magic trick to intentionally freezes themselves and immobilize the water in their cells,” says Nakano, who also holds an appointment with USC’s Department of Biological Sciences.

“The frozen cells cannot be disturbed by any radiation or chemical process and it also protects the DNA, so the spores can continue to reproduce.”

According to the researchers’ models, a combination of heat and moisture “defrosts” the water inside the cell, returning it to a liquid form. Without this protective barrier, the spore is more easily destroyed.

The computer models also allowed the researchers to determine the exact temperature and water balance needed to destroy the bacteria: between 90-95 degrees Celcius with a water concentration above 30 percent.

These insights could be used to prevent microbial contamination on food processing equipment and limit the spread of disease in the event of a biological attack. And because the process relies on moist-heat rather than chemical processes, the bacteria shouldn’t be able to develop resistance.

The paper, entitled “Gel phase in hydrated calcium dipicolinate,” appeared in Applied Physics Letters. The research was supported by the Defense Threat Reduction Agency.

Contacts and sources:
Caitlin Dawson
USC Viterbi


Source: http://www.ineffableisland.com/2018/02/best-way-to-kill-deadly-bacteria.html


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    • Everette

      The best way to kill bacteria and viruses comes from 4 different but powerful methods . The first was discovered in the middle ages when thieves were robbing dead victims jewlery caused by the bubonic plague . They were herbalist . When they were finally caught the king threatened them with death or reveal their secret . The thieves had put together a mix of Lemon oil , Eucalyptus oil , clove , cinnamon and rosemary oil . The blend was a powerful but poteint elixir . Putting a drop on a cotton swab and placing in front of a fan kills 98.99 bacteria and viruses in the room by just circulation , its been tested . The thieves had placed it on their clothes and near their faces with mask so they could breath it in . They probably even injested it . It’s just food ! The next powerful bacteria , virus killer was discovered in the early 1900 by a man named Rife . He had discovered that every thing continued or was a frequency . Under the microscope he discovered that if he could find the frequency a bacteria or virus vibrated at and send frequencies of the same Hz in greater amounts it would over vibrate the germ and blow it to pieces . Kind of like the opera singer hitting the same note the glass vibrates at and over resounding it , it explodes . Rife took a 1000 stage 4 on their death bed cancer patients and found the frequency of the cancers they had and destroyed the cancer in every patient . The government found out and raided his lab and stole his records . Big pharma and doctors felt threatened and had the authorities close down his lab . The next powerful solution is called silver water . Made by electrolysis of silver into water at low voltage ( 9volt works well ) . Take 2 strands of silver and add positive voltage on one and negative voltage on the other , add a small sprinkle of salt to make the electrolyte . Keep the wire separated . A small fog will begin to cloud the water . Run it for about 15 minutes . Then remove the wire and battery . Shake well , then use on wound or drink a mouth full and refrigerate the rest to keep from tarnishing and turning the water dark . It has been tested on 650 bacteria and viruses known to man and killed them within 5 minutes . It collapses the breath part of the bacteria or viruses just by contact . The last but not the least is electricity . My brother had the swine flu . He was hospitalized . Finally he was released after . But it relapsed . It was a Sunday and he felt so bad that he stated he was going to the doctor the next morning . I had put together a light switch and wired it to a 9volt battery inside . It had 2 lead wires . One I hooked to his toe the other to his head . I knew he would not let me flip the switch but a few times so I employed his wife . I added water to both leads . Without the water you can not feel anything hardly , but with the water it sends tingles through you . I had his wife flip the switch 50 times on and off . After that I said it is done . I checked on him the next day , he was outside busting wood and felt great . He did not return to the doctor for the swine flu . Even the coughing had subsided . Electricity kills bacteria and viruses . Simple things with powerful results . I have even used them on cancer patients . Cancer starts with a viruses that ends up mutating the cells . One more goody ! Find someone with an ionic detox machine . It runs negative electrons thru you grabbing all loose items inside of you and drags it out thru your feet into a tub of water your feet are setting in . I have pulled out worms , oil , cancer blob , metals and many other things from people . So why don’t these smart people we call doctors and pharmacist use these devices ? Because radiation treatment and chemo pills and liquid give them a hell of a lot more money . It has been said when they find something that is worse than cancer and will make more money , then they will release the cure for cancer ! Think about this ! A person going to school to be a doctor will have to go from 8 to 12 years to school depending on what the position is to be . Now taking a low payment for collage at $50,000 a year then adding housing and food we come up with about $70,000 a year . So let say that peron attends for 10 years . If this person borrowed this money from the government that person will owe $700,000 dollars without interest . After interest we could be talking $1,000,000 ( 1 million dollars ) or more . Now this doctor has to pay back that loan . How do you think they are going to accomplish this task ? They must get clients Or find a hospital willing to pay outragis pay . To get the money paid back more quickly the doctor will try and start their own business . So once obtaining his clients , if they don’t return he will soon be out of business . Make them well and they may never get anything that will bring them back to the doctor . So we have follow ups , then probe deeper . OK ! The doctor has found something small but pills will help . But these pills have effects and cause some other problem . Now the patient is on more pills and needs more follow ups to keep checkups on side effects . Once checked again the patient now has more problems . Big pharm ask this question , how can we sell more drugs so we can make more money . Their answers were create an addicting drug , create a drug that will solve the problem it was prescribed for but will cause other problems . Inject the patient with vaccines with viruses and bacteria and tell them the strains are weak or tell them there is no viruses in it . But don’t tell them there are 10 different strains of bacteria and viruses in the vaccine and Added mercury and Aluminium for toxicity . This toxic mess of added metals will cause problems down the road which will sell more drugs . Next time you go into a big city count how mant pharmacies you find . And take note how close they are and many are still being built . Are you beginning to get my point ? We are their ginny pigs . So they lose a few trying to get the perfect streak of sickness that will bring in train loads of money . People are making babies all the time so we dont have to worry for awhile . Then the pharma pays the doctors a percentage for ever prescription they sell . Wow ! This loan is headed for a quick pay off ! Have you ever felt that you are just a number and not really a person ? Well their actions are done to make you feel that way . When you come back to your senses , you then begin asking questions which they don’t like answering ! Then on top of things frequencies can also attract bacteria and viruses . ELF towers are set up everywhere . They are running brain wave frequencies and killer bacteria and virus frequencies . Then to add to that thy are spraying you with chemicals from airplanes . Watch them turn the trails on and off . Nearing a city or town it is turned on and leaves a streat across the sky . After going over the city or town it is turned off and the streak stops . I have read there is blood , bacteria , viruses Metals , fungus , blitz and molds being sprayed on us . Then recently planes are now dumping their holding tanks with poop and piss on top of us ! My house was hit with some and their blue water . And mud puddles now stink like a septic tank . These people doing this need to be found and shot on the spot and those in high places ordering it also ! This is crimes against humanity ! I have found that the liberal democrats are some of you biggest sponcers of it . The natzi NWO reptilian Vatican has ordered it as well as the Muslim UN . It’s time we put a stop to their evils ! Those with the knowledge of who and how need to start dropping names and places to the public until action is taken to stop these evils ! We the people own this country , not the few we send to Washinton or to our capitols to help govern our country following our wishes . Somewhere between leaving our state and reaching Washington they loose their minds and forget who they are and why we sent them !!!

    • holeshot

      Without a doubt there is only one proven way to kill bacteria. Simply set one side of your body on fire and when all the bacteria run to the other side you stab them with an ice pick. We all need bacteria to live, especially in the gut, and the practice of using antibiotics for every little hiccup only prevents the body from building up an immunity to bad bacteria and allows the bacteria to develop an immunity to the drugs so as to render them ineffective when REALLY needed. Let your body fight most things off naturally and save the heavy artillery for when really needed. Spit on it and rub dirt on it.

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