Detoxification - How to Detox and Rejuvenate Your Skin Appearance, Citations Provided by Medline Studies

By Kyle J. Norton, Scholar, Master of Nutrition

Skin is a largest organ in the body with function to protect the internal organs and tissue against foreign organisms infection, leading organs and tissue injure and damage.

It also is third organ behind liver and kidney to eliminate body toxins if the first 2 fail to cleanse them all.

Western diet contains high saturated fat, trans fat, and other harmful substances such as sugar, caffeine, pesticides, additive substances, and less in fruits and vegetables. 

These types of harmful substances are toxic. Our body’s detoxifying functions try to get rid of them everyday. 

However, if they are overwhelmed, over expression of toxins can induce a disruption of hormone production, damage the body’s detoxification organs and weaken the immune system, affecting in hormone balancing and exhibiting varieties of chronic illness consequently. 

Natural Skin cleansing remedies may include

1. Selenium
Selenium is very important  mineral in rejuvenating skin condition.

Dietary selenium not only protects skin against photo damage but, as a topical application, it also improves skin surface parameters(2).

The supplementation has been proposed to confer health benefits for patients suffering from some viral diseases. And in vitro, intake of selenium exerted a profound effect in inhibited progression of over growth Candida albicans organisms of selenium deficiency rats in induction of toxins accumulation(3).

There is a relative incidence of Candida albicans on the skins of persons with skin diseases(4).

In Psoriasis patients, application of selenium decreased levels of reactive oxygen species through inhibiting production of proinflammatory cytokine tumor necrosis factor alpha (TNF-α). As the result, the mineral also protect skin against the external factor, ultraviolet B (UVB) radiation in affecting the skin health(1).

Furthermore, selenium can also influence immune response by changing the expression of cytokines and their receptors found in the outer layer of skin cells and making immune cells more resistant to oxidative stress(1).

2. Zinc supplementation
Zinc is the third highest abundance in the skin of the body, particularly, in the epidermis and the dermis.

The mineral also is a powerfully natural antibiotic used in cosmetic products for treatment of acne(5) and other forms of skin diseases, caused by skin inflammation and toxins accumulation by stimulating the release of vitamin A from the skin.

Oral administration of zinc sulphate is effective for patients with long term parenteral hyperalimentation developed skin lesions, similar to those seen in acrodermatitis enteropathica(6).

According to the University of Yamanashi, zinc deficiency may reduce the active proliferation and differentiation of epidermal keratinocytes in induction of skin disorder(7).

3. Lecithin

Lecithin is a fat-like substance, or phospholipid, produced by healthy liver. It is needed for a healthy skin.

Lecithin helps the body in utilizing vitamins A, D, E in fighting against the bacteria and virus that causes skin problems(9). The antioxidant also eliminate the toxins on the skin or around the eyes caused by fatty deposits(10).

Application of poly(lactide-co-glycolide) (PLGA) and lecithin/chitosan (LC) nanoparticles enhanced the amount of betamethasone-17-valerate  in epidermis as formulation for topical application for steroidal treatment(11).

4. Strawberry

Strawberries come in endless varieties but all leaves of all strawberries contain healing tannins.

The herb has also been used to aid in the treatment of anemia, eczema, jaundice and other skin problems caused by weakening of the liver.

According to the joint study lead by the Polytechnic University of Marche, strawberry-based cosmetic products showed a substantial effect to reduce skin damage caused by exposed to environmental stressors, such as UVA radiation in induction of oxidative stress, inflammation and cell death via the production of reactive oxygen species (ROS)(12).

Additionally, products containing strawbery also protect skin in stimulated production of human dermal fibroblasts (HDF) in forming the connective tissue of the skin during wound healing(12).

5. Burdock root

Burdock has traditionally been used in treating chronic skin ailments such as eczema psoriasis, and dermatitis through its antioxidant, anti-inflammatory, and antibacterial compounds(13).

The herb also has a significant effect in purified the bloodstream of toxins that can lead to skin diseases(13).

According to the National Cancer Institute, quercetin, the major antioxidant isolated from burdock root are capable of mitigating radiation induced skin fibrosis(14).

As Western blotting assay showed that quercetin treatment significantly reduced hind limb contracture, collagen accumulation and expression of TGF-β caused by toxicity of irradiated skin(14)
in exhibited loss of function due to reduced range of motion and pain.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Selenium and psoriasis by Nazıroğlu M1, Yıldız K, Tamtürk B, Erturan İ, Flores-Arce M(PubMed)
(2) Selenoproteins are essential for proper keratinocyte function and skindevelopment by Sengupta A1, Lichti UF, Carlson BA, Ryscavage AO, Gladyshev VN, Yuspa SH, Hatfield DL(PubMed)
(3) An in vivo and in vitro study of selenium deficiency and infection in rats, by Boyne R, Arthur JR, Wilson AB(PubMed)
(4) Relative incidence of Candida albicans on the skins of persons with and without skin diseases by MARWIN RM(PubMed)
(5) The role of zinc in the treatment of acne: A review of the literature by Cervantes J1, Eber AE1, Perper M1, Nascimento VM1, Nouri K1, Keri JE(PubMed)
(6) Acquired zinc deficiency disease of skin by Wexler D, Pace W(PubMed)
(7) Zinc and skin biology by Ogawa Y1, Kawamura T2, Shimada S(PubMed)
(9) [The effect of lecithin type on the absorption of vitamins A and E from liposomes in the skin].[Article in German] by Szulc J1, Woyczikowski B, Szczepanska M, Cal K, Wolniak L, Sosada M, Pasker B, Wasowicz K(PubMed)
(10) Integrating Complementary Medicine into Veterinary by PracticeBy Paula Jo Broadfoot, Richard E. Palmquist,
(11) Comparison of PLGA and lecithin/chitosan nanoparticles for dermal targeting of betamethasone valerate by Özcan I1, Azizoğlu E, Senyiğit T, Özyazici M, Özer Ö(PubMed)
(12) A Pilot Study of the Photoprotective Effects of Strawberry-Based CosmeticFormulations on Human Dermal Fibroblasts by Gasparrini M1, Forbes-Hernandez TY2,3, Afrin S4, Alvarez-Suarez JM5,6, Gonzàlez-Paramàs AM7, Santos-Buelga C8, Bompadre S9, Quiles JL10, Mezzetti B11, Giampieri F(PubMed)
(13) Top 15 Herbs that Push Psoriasis Out of Your Space!(Natural On)
(14) Quercetin inhibits radiation-induced skin fibrosis by Horton JA1, Li F, Chung EJ, Hudak K, White A, Krausz K, Gonzalez F, Citrin D(PubMed)