JAMA STUDY: Depression: An Adverse Effect of Prescription Medication

Armed with Knowledge

IMPORTANCE: Prescription medications are increasingly used among adults in the United
States and many have a potential for causing depression.
OBJECTIVES: To characterize use of prescription medications with depression as a potential
adverse effect and to assess associations between their use and concurrent depression.

Prescription medications are widely and increasingly
used in the United States, with approximately 15% of
adults estimated to have been using 5 or more concurrent
prescription medications in 2011 and 2012.1 Alongside evidence
that adverse drug events from prescription medications
are often implicated in emergency department visits and
hospitalizations,2 there is gaining recognition thatmany commonlyused
prescriptionmedications, includinghormonalcontraceptives
and β-blockers, are associated with an increased
risk of depression.

CONCLUSION: In this cross-sectional survey study, use of prescription
medications that have depression as a potential adverse effect was common. Use of multiple
medications was associated with greater likelihood of concurrent depression.

Read study:  JAMA_drugs_linked_to_depression(1)

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