Who is St. Peregrine, the ‘cancer saint’ Catholics are invoking for Pope Leo XIV?

As Pope Leo XIV recovers at Rome’s Gemelli Hospital from surgery that confirmed lung cancer, Catholics around the world are praying for him, and many are turning to a 14th-century Servite priest long known as “the cancer saint”: St. Peregrine Laziosi.

From punch to penance

According to an account by Father Lawrence G. Lovasik, SVD, published in EWTN’s library, Peregrine was born in 1260 in Forlì, Italy. He was the only son of a wealthy family, and as a young man he sided with the city’s anti-papal faction.

When St. Philip Benizi of the Servants of Mary (the Servites) came to Forlì to preach peace on behalf of Pope Martin IV, he was met with insults, rocks, and clubs. Peregrine struck him in the face. Philip answered by offering the other cheek and praying for the young man.

Moved, Peregrine ran after the departing friar. He begged forgiveness on his knees and promised to change his life. According to the traditional account, the Virgin Mary later appeared to him in Forlì’s cathedral and told him: “Go to Siena. There you will find the devout men who call themselves my servants. Join them.”

Peregrine received the Servite habit in 1292. It was said that for 30 years he never sat down. In 1322, his superiors sent him to found a Servite house in his hometown of Forlì, where he became known as a preacher and a readily available confessor.

The night before the amputation

Later in life, Peregrine developed a painful cancerous wound on his foot. Lovasik writes that its “gangrenous stench” was so foul that others kept away. Surgeons decided to amputate.

Peregrine spent the night before the operation in prayer before an image of the crucified Christ and fell asleep there. In a dream, Christ seemed to reach down from the cross and touch his diseased foot. When he awoke, he was healed. The account says the doctors could no longer find any trace of the disease.

Peregrine died in 1345 at about 80 years of age. He was beatified in 1609, and Pope Benedict XIII canonized him in 1726. His feast is celebrated May 1. His body rests in the Basilica of San Pellegrino Laziosi in Forlì. Devotion to him has spread far beyond Italy, including to the National Shrine of St. Peregrine at Our Lady of Sorrows Basilica in Chicago, the city where Leo was born.

Lovasik’s booklet includes several prayers, and EWTN offers a novena to St. Peregrine.