Seelos Therapeutics files new drug application for a Sanfilippo syndrome study
Seelos Therapeutics Inc (NASDAQ:SEEL) is one step closer to launching a Phase 2b/3 clinical study for the treatment of Sanfilippo syndrome.
The company has filed an Investigational New Drug application with the US Food and Drug Administration for a clinical study of its drug SLS-005, also known as Trehalose.
Seelos is collaborating with Team Sanfilippo Foundation, a non-profit foundation formed by parents of children with the condition. The foundation provided a grant that is going towards funding the study.
READ: Seelos Therapeutics receives funding grant from Team Sanfilippo Foundation
The parties are also expanding the study from its original parameters. In addition to the study for patients with Sanfillipo syndrome types A and B, which are more common, Seelos is now able to offer a separate expanded access study for patients with types C and D, as well as those with A or B who don’t meet the initial entry criteria.
“We are very excited to be working with Team Sanfilippo to offer this innovative therapy to these patients for whom there is no effective treatment,” Seelos’ Chief Medical Officer Warren Wasiewski said. “Trehalose, with its multiple mechanisms of action, has the potential to be effective in a number of neurologic diseases for which we intend to explore.”
Sanfilippo syndrome is a degenerative disease that affects the central nervous system, typically in children. It is caused by a deficiency in certain enzymes involved in the degradation of sulfate. Over time, patients suffer a loss of speech and other cognitive skills, heart problems and often death prior to adulthood.
Contact Andrew Kessel at [email protected]
Follow him on Twitter @andrew_kessel
Story by ProactiveInvestors
Source: https://www.proactiveinvestors.com/companies/news/224068/seelos-therapeutics-files-new-drug-application-for-a-sanfilippo-syndrome-study-224068.html
Anyone can join.
Anyone can contribute.
Anyone can become informed about their world.
"United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.
Please Help Support BeforeitsNews by trying our Natural Health Products below!
Order by Phone at 888-809-8385 or online at https://mitocopper.com M - F 9am to 5pm EST
Order by Phone at 866-388-7003 or online at https://www.herbanomic.com M - F 9am to 5pm EST
Order by Phone at 866-388-7003 or online at https://www.herbanomics.com M - F 9am to 5pm EST
Humic & Fulvic Trace Minerals Complex - Nature's most important supplement! Vivid Dreams again!
HNEX HydroNano EXtracellular Water - Improve immune system health and reduce inflammation.
Ultimate Clinical Potency Curcumin - Natural pain relief, reduce inflammation and so much more.
MitoCopper - Bioavailable Copper destroys pathogens and gives you more energy. (See Blood Video)
Oxy Powder - Natural Colon Cleanser! Cleans out toxic buildup with oxygen!
Nascent Iodine - Promotes detoxification, mental focus and thyroid health.
Smart Meter Cover - Reduces Smart Meter radiation by 96%! (See Video).