The Effect of Obesity on the Level of Fractional Exhaled Nitric Oxide in Children with Asthma
Home of Kyle J. Norton for The Better of Living & Living Health Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese. Clinically Overweight and obesity are defined indicators of a disease process characterized by the accumulation of body fat due to an excess of energy intake (nutritional intake) relative to energy expenditure (physical activity)(a).
The Effect of Obesity on the Level of Fractional Exhaled Nitric Oxide in Children with Asthma
In the study to to evaluate the association of FeNO with obesity and obesity-related metabolic complications in asthmatic and nonasthmatic children, included children aged between 6 and 17 years and consisted of 4 groups: obese asthmatics (n = 52), normal-weight asthmatics (n = 49), obese nonasthmatics (n = 51) and normal-weight nonasthmatics (n = 42), showed that the FeNO level of asthma patients with MS was not different from those without MS (14.5 ± 8.0 and 16.7 ± 8.7, respectively, p = 0.449). In the nonasthmatic group, subjects with MS had a higher FeNO level than subjects without MS (12.5 ± 5.1 and 17.3 ± 8.3, respectively, p = 0.014). Spearman’s rank correlation coefficients revealed a positive correlation between FeNO and body mass index (BMI; p = 0.049, r2: 0.204) in the nonasthmatic group and after multivariate regression analysis, BMI still persisted as an independent risk factor for FeNO and conclude that a positive correlation between BMI and FeNO level which suggests a link between obesity and increased airway inflammation in nonasthmatic children(15).
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(15) http://www.ncbi.nlm.nih.gov/pubmed/23921526
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Source: http://medicaladvisorjournals.blogspot.com/2013/10/the-effect-of-obesity-on-level-of.html
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