A New Avenue for Treating Insomnia
Insomnia is one of the major sleep problems with an estimated prevalence of 10% to 15% in the general population and 30% to 60% in the older population.
A new therapeutic avenue for treating insomnia
Although mice are the most commonly usedmodel organismof human disease, results in mice, however, are often not always reliable for predicting human study outcomes. Therefore, “many obstacles remain to be overcome in generating a novel drug for the treatment of insomnia in humans, but we believe that our discovery will unlock the development of the next-generation sleeping pill.” explained medicinal chemist Dr. Tsuyoshi Saitoh, another lead author of the paper.
About IIIS
IIIS was launched by the Ministry of Education, Culture, Sports, Science and Technology of Japan with the aim of building globally visible research centers with high research standards and excellent research environments to accommodate globally prominent researchers. IIIS is the world’s premier institute aiming to elucidate the fundamental principles of sleep/wake biology, develop new strategies to diagnose, prevent, and treat sleep disorders, and contribute to promote human health through research activities. The research was funded by the Japan Society for the Promotion of Science and the Japan Science and Technology Agency.
Contacts and sources:
University of Tsukuba
Citation: Korkutata M., Saitoh T., Cherasse Y., Ioka S., Duo F., Qin R., Murakoshi N., Fujii S., Zhou X., Sugiyama F., Chen JF., Kumagai H., Nagase H., and Lazarus M., (2018) Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function.
Neuropharmacology
doi: 10.1016/j.neuropharm.2018.10.022 .
Source:
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Being an insomniac, I’m always glad to discover new information about the treatment of sleep issues. A lot of people take sleeping pills. Of course, they work, but such medications can be taken only during a short period of time (I double-checked this info on the Canada Drugs Direct site). I prefer using natural ways like monitoring my nutrition, doing sports, organizing my day in a proper way, drinking more water, etc. I hope the mentioned research will give good final results.