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Vitamin D Supplementation: This Is Why It Can Be Wrong

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October 16th, 2020

By Raluca Schachter

Contributing writer for Wake Up World

Over the past decade, vitamin D has distinguished itself as a miracle supplement. Hundreds of research studies suggest that vitamin D can help prevent a multitude of conditions, from osteoporosis to autoimmune disorders, immune function, cardiovascular disease, cancer and more.

Statistics suggest that a large number of adults and children do not have enough vitamin D in the body.

Many doctors and nutritionists routinely prescribe supplements with high doses of vitamin D, ranging from 2,000-10,000 IU (international units) per day to 50,000 IU per week.

Vitamin D obviously supports human health. But why not address the reasons behind the decline in vitamin D?

There is already solid evidence that testing and correcting vitamin D deficiency is much more complex than monitoring hydroxyvitamin D levels and vitamin D3 supplementation. This approach loses sight of the fact that many factors will mediate how 25-hydroxyvitamin D is converted to the active secosteroid hormone calcitriol (1,25-dihydroxyvitamin D) and the most potent metabolite of vitamin D. In addition, many pathogenic influences will alter the course of intracellular transport of calcitriol and nuclear binding to the vitamin D receptor (VDR).


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