Read the Beforeitsnews.com story here. Advertise at Before It's News here.
Profile image
By California Institute for Regenerative Medicine (Reporter)
Contributor profile | More stories
Story Views
Now:
Last hour:
Last 24 hours:
Total:

Bringing embryonic stem cell transplants closer to reality by quieting the immune response

% of readers think this story is Fact. Add your two cents.


A novel way of suppressing the immune system could make transplants of human embryonic stem cells a clinical possibility, according to new research by Stanford stem cell scientists.

Human embryonic stem cells (hESC) offer a tantalizing prospect for new therapies, but first we have to figure out how to get them past our immune system’s defenses. Stem cell scientists had initially thought embryonic stem cells might fly under the immune system’s radar, but a few years ago, they were surprised to find that, much like organ transplants, hESC provoke a rapid response when transplanted into a mouse’s body. When transplanted into a mouse, hESCs all died within a few days, according to previous work by the same team at Stanford, led by Joseph Wu.

But in a study published last week in the scientific journal, Stem Cells, the team used a pair of antibodies that blocked normal T-cell activation – the cells responsible for mounting the attack on foreign particles. This method worked better than the drugs traditionally used to suppress immune responses to organ transplants.

But unlike organ transplant drugs, which often need to be taken for the rest of a transplant recipient’s life, the dual-antibody treatment for hESC transplants was only needed for about a week.

On their blog, Stanford quoted Wu talking about the issue of getting the body to accept a transplant of cells derived from embryonic stem cells:

“Regenerative therapies hold great clinical promise, particularly for patients with damaged hearts and end-stage heart failure. But, surprisingly, promoting long-term stem cell graft acceptance is a much more formidable task than is supporting host acceptance of a vascularized solid organ such as a heart.”

These initial results are good news, but much more work is needed to find out if this treatment will work the same way in people as it does in mice. If the technique is effective in humans, it will help advance Wu’s ongoing work developing stem therapies for heart disease.

CIRM funding: Joseph Wu (DR2-05394, TR3-05556)

Rina Shaikh-Lesko

Read more stem cell research news from the California Institute for Regenerative Medicine by visiting our blog at cirmresearch.blogspot.com.

Learn more about the California Institute for Regenerative Medicine


Source: http://cirmresearch.blogspot.com/2013/08/bringing-embryonic-stem-cell.html


Before It’s News® is a community of individuals who report on what’s going on around them, from all around the world.

Anyone can join.
Anyone can contribute.
Anyone can become informed about their world.

"United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.

Humic & Fulvic Liquid Trace Mineral Complex

HerbAnomic’s Humic and Fulvic Liquid Trace Mineral Complex is a revolutionary New Humic and Fulvic Acid Complex designed to support your body at the cellular level. Our product has been thoroughly tested by an ISO/IEC Certified Lab for toxins and Heavy metals as well as for trace mineral content. We KNOW we have NO lead, arsenic, mercury, aluminum etc. in our Formula. This Humic & Fulvic Liquid Trace Mineral complex has high trace levels of naturally occurring Humic and Fulvic Acids as well as high trace levels of Zinc, Iron, Magnesium, Molybdenum, Potassium and more. There is a wide range of up to 70 trace minerals which occur naturally in our Complex at varying levels. We Choose to list the 8 substances which occur in higher trace levels on our supplement panel. We don’t claim a high number of minerals as other Humic and Fulvic Supplements do and leave you to guess which elements you’ll be getting. Order Your Humic Fulvic for Your Family by Clicking on this Link , or the Banner Below.



Our Formula is an exceptional value compared to other Humic Fulvic Minerals because...


It’s OXYGENATED

It Always Tests at 9.5+ pH

Preservative and Chemical Free

Allergen Free

Comes From a Pure, Unpolluted, Organic Source

Is an Excellent Source for Trace Minerals

Is From Whole, Prehisoric Plant Based Origin Material With Ionic Minerals and Constituents

Highly Conductive/Full of Extra Electrons

Is a Full Spectrum Complex


Our Humic and Fulvic Liquid Trace Mineral Complex has Minerals, Amino Acids, Poly Electrolytes, Phytochemicals, Polyphenols, Bioflavonoids and Trace Vitamins included with the Humic and Fulvic Acid. Our Source material is high in these constituents, where other manufacturers use inferior materials.


Try Our Humic and Fulvic Liquid Trace Mineral Complex today. Order Yours Today by Following This Link.

Report abuse

    Comments

    Your Comments
    Question   Razz  Sad   Evil  Exclaim  Smile  Redface  Biggrin  Surprised  Eek   Confused   Cool  LOL   Mad   Twisted  Rolleyes   Wink  Idea  Arrow  Neutral  Cry   Mr. Green

    MOST RECENT
    Load more ...

    SignUp

    Login

    Newsletter

    Email this story
    Email this story

    If you really want to ban this commenter, please write down the reason:

    If you really want to disable all recommended stories, click on OK button. After that, you will be redirect to your options page.