About prebiotic counterparts of tRNA and metabolic machinery

The question about the prebiotic counterparts of tRNA and tRNA-amino acid pairing stimulates also questions about the prebiotic counterpart of metabolic machinery.

What can one say about pre-tRNA?

What could be the prebiotic counterpart of tRNA in the TGD framework?

1. DtRNA should have a molecular counterpart. The simplest guess is that it corresponds to an RNA type codon appearing in tRNA but somehow differing from it. Pre-tRNA could simply be the (AAC-H)3′ end of the acceptor stem with AAC replaced with XYZ, where ZYZ denotes the codon part of tRNA. The addition of a hydrogen atom would relate pre-tRNA codon to ordinary RNA codon.
2. The bond energy for the pre-tRNA-AA pair as the energy of the ester bond would be about .5 eV, which corresponds to the metabolic energy quantum. Energy is therefore required to “charge” pre-tRNA. This requires metabolic energy and in the absence of ATP machinery, the energy should come from its predecessor. What prebiotic metabolism could be, will be discussed in the next section.
3. If this step works, the polymerization of tRNAs involving the transformation of the ester bond of pre-tRNA-AA to AA-AA peptide bond can occur spontaneously since the peptide bond has bond energy of order .1 eV. This would give rise to polypeptides. This process would be like a translation process for RNA but without an RNA template and therefore the outcome would be random. Also the RNA polymerization in this manner can be considered, now however the RNA-RNA valence bond has considerably higher bond energy.
4. If DRNA-RNA sequences are formed, they might be transformed to AA sequences by pre-translation process using pre-tRNA and resonance mechanism pairing DRNAs and dark counterparts of pre-tRNA-AA pairs. This would define the pre-translation process.

What could the prebiotic metabolic machinery be?

Metabolic machinery should have a prebiotic counterpart and have .5 eV as metabolic energy quantum.

1. Could the splitting of a hydrogen bond with bond energy about .5 eV provide the energy needed in the formation of pre-tRNA-AA ester bond? IR photons are most effective in causing Pollack effect in water: could also they induce pre-tRNA-AA pairing? Both options would require the presence of water. In principle, the proposed mechanism could lead to a generation of water molecules (the energy of O-H bond is 4.81 eV) already at temperatures of few Kelvin.
2. Could MB somehow provide the metabolic energy quantum? Gravitational flux tubes are in a central role in the TGD inspired quantum biology. the gravitational binding energy of a nucleon in the gravitational field of Earth is .67 eV (see this). This is somewhat larger than the metabolic energy quantum. A dark proton at a distance of about .34 R_E, R_E Earth radius, from the surface of Earth has gravitational binding energy of .5 eV.

The bond energy of the hydrogen bond is .5 eV. Could it correspond to the reduction of the gravitational binding energy due to the delocalization of a dark proton to a gravitational flux tube? Could the hydrogen bond become dark with h_eff= h_gr. The transformation of a dark proton at the gravitational flux tube of MB to an ordinary proton implies a localization having interpretation as falling to the surface of Earth. Could this provide the metabolic energy quantum?

For a summary of earlier postings see Latest progress in TGD.

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