Antiviral effect of high-dose Ivermectin in adults with COVID-19: A proof-of-concept randomized trial
AbstractBackground There are limited antiviral options for the treatment of patients with COVID-19. Ivermectin (IVM), a macrocyclic lactone with a wide anti-parasitary spectrum, has shown potent activity against SARS-CoV-2 in vitro. This study aimed at assessing the antiviral effect of IVM on viral load of respiratory secretions and its relationship with drug concentrations in plasma. Methods Proof-of-concept, pilot, randomized, controlled, outcome-assessor blinded trial to evaluate antiviral activity of high-dose IVM in 45 COVID-19 hospitalized patients randomized in a 2:1 ratio to standard of care plus oral IVM at 0·6 mg/kg/day for 5 days versus standard of care in 4 hospitals…
Source: http://freedombunker.com/2021/07/17/antiviral-effect-of-high-dose-ivermectin-in-adults-with-covid-19-a-proof-of-concept-randomized-trial/
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