Sarepta Crashes After Second Death On Gene Therapy Drug
Sarepta Therapeutics shares suffered their steepest drop in years on Monday morning after a second teenage patient died following treatment with Elevidys, the biotech’s one-time gene therapy for Duchenne muscular dystrophy (DMD).
“These steps follow a second reported case of acute liver failure (ALF) resulting in death. The cases of ALF to date have both occurred in non-ambulatory individuals with Duchenne. Sarepta extends its deepest sympathies to the affected families and care teams,” Sarepta wrote in a press release.
In response, Sarepta suspended 2025 revenue guidance and will “take a careful look” at its costs moving forward, CEO Doug Ingram told Wall Street analysts on a call. The second loss of life will intensify the Food and Drug Administration’s scrutiny of the FDA‑approved, prescription gene therapy available commercially in the U.S. and several other countries.
Goldman healthcare analyst PJ Gallo told clients earlier:
Second Patient Death on ELEVIDYS Drives Weakness: The company reported a second case of acute liver failure that resulted in death in a non-ambulatory individual with DMD who received ELEVIDYS. Recall the first death was reported back in mid-March. Shipments of ELEVIDYS for non-ambulatory patients were suspended as a result. And dosing for the company’s ENVISON study was voluntarily paused.
Cantor Fitzgerald analyst Kristen Kluska stated:
“We think a second death is going to dramatically impact physician, caregiver and patient decisions moving forward.”
There were notable Street actions: SRPT Sarepta Cut to Neutral at Piper Sandler; PT $36, Sell at HC Wainwright; PT $10, Neutral at Piper Sandler; PT $36, Market Perform at BMO; PT $70
Sarepta shares crashed as much as 48% in the U.S. morning, the most since Jan. 8, 2021.
Roundtrip.
Thanks for playing.
Tyler Durden Mon, 06/16/2025 – 13:25
Source: https://freedombunker.com/2025/06/16/sarepta-crashes-after-second-death-on-gene-therapy-drug/
Anyone can join.
Anyone can contribute.
Anyone can become informed about their world.
"United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.
Before It’s News® is a community of individuals who report on what’s going on around them, from all around the world. Anyone can join. Anyone can contribute. Anyone can become informed about their world. "United We Stand" Click Here To Create Your Personal Citizen Journalist Account Today, Be Sure To Invite Your Friends.
LION'S MANE PRODUCT
Try Our Lion’s Mane WHOLE MIND Nootropic Blend 60 Capsules
Mushrooms are having a moment. One fabulous fungus in particular, lion’s mane, may help improve memory, depression and anxiety symptoms. They are also an excellent source of nutrients that show promise as a therapy for dementia, and other neurodegenerative diseases. If you’re living with anxiety or depression, you may be curious about all the therapy options out there — including the natural ones.Our Lion’s Mane WHOLE MIND Nootropic Blend has been formulated to utilize the potency of Lion’s mane but also include the benefits of four other Highly Beneficial Mushrooms. Synergistically, they work together to Build your health through improving cognitive function and immunity regardless of your age. Our Nootropic not only improves your Cognitive Function and Activates your Immune System, but it benefits growth of Essential Gut Flora, further enhancing your Vitality.
Our Formula includes: Lion’s Mane Mushrooms which Increase Brain Power through nerve growth, lessen anxiety, reduce depression, and improve concentration. Its an excellent adaptogen, promotes sleep and improves immunity. Shiitake Mushrooms which Fight cancer cells and infectious disease, boost the immune system, promotes brain function, and serves as a source of B vitamins. Maitake Mushrooms which regulate blood sugar levels of diabetics, reduce hypertension and boosts the immune system. Reishi Mushrooms which Fight inflammation, liver disease, fatigue, tumor growth and cancer. They Improve skin disorders and soothes digestive problems, stomach ulcers and leaky gut syndrome. Chaga Mushrooms which have anti-aging effects, boost immune function, improve stamina and athletic performance, even act as a natural aphrodisiac, fighting diabetes and improving liver function. Try Our Lion’s Mane WHOLE MIND Nootropic Blend 60 Capsules Today. Be 100% Satisfied or Receive a Full Money Back Guarantee. Order Yours Today by Following This Link.
