Proteins are not normally found in the urine of healthy individuals as the filtering units of the kidney prevent the loss of large proteins and smaller ones are typically reabsorbed. A team of researchers at the University of Sao Paulo in Brazil and Ohio State University recently searched for biomarkers indicative of early stages of kidney disease in dogs. They discovered that the urine of dogs in stages 1 or 2 of chronic kidney disease contained vitamin D-binding proteins and retinol-binding proteins. By stage 4 the presence of Tamm-Horsfall protein in the urine had declined. Vitamin D-binding protein is responsible for transporting vitamin D in the blood. Perhaps not surprisingly, therefore, some studies have found that vitamin D deficiency may be associated with the progression of chronic kidney disease. Similarly, retinol-binding protein transports retinol from the liver to the blood. Tamm-Horsfall protein, on the other hand, is a normal constituent of urine and is thought to help prevent the formation of calcium oxalate kidney stones. Thus lower levels of this protein in urine is a marker of more advanced kidney disease.
F Chacar, M Kogika, TR Sanches, D Caragelasco, C Martorelli, C Rodrigues, JMC Capcha, D Chew, L Andrade. Urinary protein, albumin, vitamin D-binding protein, and retinol-binding protein as early biomarkers of chronic kidney disease in dogs. Physiological Reports. Vol. 5: no. e13262. DOI: 10.14814/phy2.13262
L Mo, HY Huang, XH Zhu, E Shapiro, DL Hasty, XR Wu. Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxacalte crystal formation. Kidney Int. 2004
Please Help Support BeforeitsNews by trying our Natural Health Products below!
Order by Phone at 888-809-8385 or online at https://mitocopper.com M - F 9am to 5pm EST
Order by Phone at 866-388-7003 or online at https://www.herbanomic.com M - F 9am to 5pm EST
Order by Phone at 866-388-7003 or online at https://www.herbanomics.com M - F 9am to 5pm EST
Humic & Fulvic Trace Minerals Complex - Nature's most important supplement! Vivid Dreams again!
HNEX HydroNano EXtracellular Water - Improve immune system health and reduce inflammation.
Ultimate Clinical Potency Curcumin - Natural pain relief, reduce inflammation and so much more.
MitoCopper - Bioavailable Copper destroys pathogens and gives you more energy. (See Blood Video)
Oxy Powder - Natural Colon Cleanser! Cleans out toxic buildup with oxygen!
Nascent Iodine - Promotes detoxification, mental focus and thyroid health.
Smart Meter Cover - Reduces Smart Meter radiation by 96%! (See Video).